Hs01061962_g1

• Gene Symbol: TLR4
• Gene Name: toll like receptor 4
• Gene Aliases: ARMD10, CD284, TLR-4, TOLL
• Chromosome Location: Chr.9: 117704175 - 117717491 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TLR4
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003266.3	NP_003257.1	2 - 3	513		121
GenBank mRNA	AK226155.1	-	2 - 3	268		121
	AK290053.1	-	2 - 3	496		121
	AL710219.1	-	2 - 3	363		121
	BC143841.1	-	2 - 3	235		121
	U88880.1	-	2 - 3	259		121

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	DA652115.1	-	2 - 3	345		Chr. 9 - 117704344 - 117708710 [+] on Build GRCh38	121
GenBankmRNA	DA659856.1	-	2 - 3	300		Chr. 9 - 117704388 - 117712498 [+] on Build GRCh38	121
GenBankmRNA	DB078565.1	-	2 - 3	286		Chr. 9 - 117704402 - 117712507 [+] on Build GRCh38	121
GenBankmRNA	DA655734.1	-	2 - 3	379		Chr. 9 - 117704311 - 117708731 [+] on Build GRCh38	121
GenBankmRNA	DA651112.1	-	2 - 3	421		Chr. 9 - 117704267 - 117708723 [+] on Build GRCh38	121
GenBankmRNA	DB069557.1	-	2 - 3	285		Chr. 9 - 117704403 - 117712485 [+] on Build GRCh38	121
GenBankmRNA	DA326784.1	-	2 - 3	241		Chr. 9 - 117704447 - 117712555 [+] on Build GRCh38	121
GenBankmRNA	AL713614.1	-	1 - 2	125		Chr. 9 - 117708197 - 117708979 [+] on Build GRCh38	121
GenBankmRNA	DA990452.1	-	2 - 3	315		Chr. 9 - 117704373 - 117712441 [+] on Build GRCh38	121
GenBankmRNA	DB148398.1	-	2 - 3	462		Chr. 9 - 117704226 - 117708668 [+] on Build GRCh38	121
GenBankmRNA	DA338581.1	-	2 - 3	496		Chr. 9 - 117704192 - 117708664 [+] on Build GRCh38	121

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	uncharacterized LOC101928797	LOC101928797		-51.2kb	Sense	Chr. 9 - 117648606 - 117657027 on NCBI Build GRCh38
Downstream	BMP/retinoic acid inducible neural specific 1	BRINP1	DBC1, DBCCR1, FAM5A	1.5mb	Anti-sense	Chr. 9 - 119166630 - 119369461 on NCBI Build GRCh38

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0900008587.hg.1
This assay targets the same location as HTA transcript cluster(s) TC09000601.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TLR4

Gene Ontology Categories:

Process(es)

regulation of cytokine production
toll-like receptor signaling pathway
B cell proliferation involved in immune response
nitric oxide production involved in inflammatory response
regulation of dendritic cell cytokine production
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
inflammatory response
immune response
I-kappaB kinase/NF-kappaB signaling
I-kappaB phosphorylation
positive regulation of platelet activation
positive regulation of gene expression
astrocyte development
detection of fungus
positive regulation of B cell proliferation
lipopolysaccharide-mediated signaling pathway
response to lipopolysaccharide
detection of lipopolysaccharide
interferon-gamma production
negative regulation of interferon-gamma production
negative regulation of interleukin-17 production
negative regulation of interleukin-23 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
positive regulation of chemokine production
positive regulation of interferon-alpha production
positive regulation of interferon-beta production
positive regulation of interferon-gamma production
positive regulation of interleukin-1 production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
negative regulation of MyD88-independent toll-like receptor signaling pathway
toll-like receptor 4 signaling pathway
TRIF-dependent toll-like receptor signaling pathway
T-helper 1 type immune response
macrophage activation
defense response to bacterium
innate immune response
positive regulation of MHC class II biosynthetic process
positive regulation of nitric oxide biosynthetic process
negative regulation of osteoclast differentiation
positive regulation of transcription by RNA polymerase II
positive regulation of JNK cascade
positive regulation of inflammatory response
defense response to Gram-negative bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
intestinal epithelial structure maintenance
positive regulation of macrophage cytokine production
necroptotic process
negative regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
cellular response to lipopolysaccharide
cellular response to lipoteichoic acid
cellular response to mechanical stimulus
apoptotic signaling pathway
positive regulation of NLRP3 inflammasome complex assembly
positive regulation of NIK/NF-kappaB signaling

Function(s)

lipopolysaccharide binding
lipopolysaccharide immune receptor activity
transmembrane signaling receptor activity
protein binding
signaling receptor activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR09006793.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09006793.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09006793.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR09006793.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR09006793.hg.1	TC09000601.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	TC0900008587.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900157288.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000355622.6	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000394487.4	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000472304.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	ENST00000490685.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_003266.3	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138554.4	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq
Affymetrix Human Clariom D Assay	TC0900008587.hg.1	NM_138557.2	Refseq