Hs01063853_m1

• Gene Symbol: IKBKE
• Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
• Gene Aliases: IKK-E, IKK-i, IKKE, IKKI
• Chromosome Location: Chr.1: 206470243 - 206496890 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: IKBKE
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001193321.1	NP_001180250.1	16 - 17	2191		67
	NM_001193322.1	NP_001180251.1	17 - 18	2310		67
	NM_014002.3	NP_054721.1	17 - 18	2310		67
	XM_005273356.2	XP_005273413.1	17 - 18	2306		67
	XM_017002868.1	XP_016858357.1	16 - 17	2306		67
GenBank mRNA	AB016590.1	-	15 - 16	1734		67
	AF241789.1	-	15 - 16	1732		67
	AK093798.1	-	11 - 12	1171		67
	BC105923.1	-	17 - 18	2058	40001562	67
	BC105924.1	-	17 - 18	2058	40001567	67
	BC107591.1	-	17 - 18	2058		67
	BC107812.1	-	16 - 17	1939	40001564	67
	D63485.1	-	17 - 18	2058		67

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0100011374.hg.1
This assay targets the same location as HTA transcript cluster(s) TC01001723.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene IKBKE

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein phosphorylation
immune response
I-kappaB phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage
negative regulation of type I interferon production
response to type I interferon
response to interferon-beta
TRIF-dependent toll-like receptor signaling pathway
NIK/NF-kappaB signaling
positive regulation of I-kappaB kinase/NF-kappaB signaling
protein homooligomerization
cellular response to virus

Function(s)

protein kinase activity
NF-kappaB-inducing kinase activity
protein binding
ATP binding
IkappaB kinase activity
ubiquitin protein ligase binding
K48-linked polyubiquitin binding
K63-linked polyubiquitin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR01026886.hg.1	TC01001723.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR01026886.hg.1	ENST00000367120.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01026886.hg.1	ENST00000462698.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01026886.hg.1	ENST00000537984.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01026886.hg.1	NM_001193321.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR01026886.hg.1	NM_001193322.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR01026886.hg.1	NM_014002.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	ENST00000578328.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	ENST00000581977.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	ENST00000584998.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	NM_001193321.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	NM_001193322.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	NM_014002.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	ENST00000578328.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	ENST00000581977.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	ENST00000584998.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	NM_001193321.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	NM_001193322.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	NM_014002.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100183623.hg.1	TC0100011374.hg.1	Clariom D TC