Hs01064523_g1

• Gene Symbol: ARHGEF2
• Gene Name: Rho/Rac guanine nucleotide exchange factor 2
• Gene Aliases: GEF, GEF-H1, GEFH1, LFP40, P40
• Chromosome Location: Chr.1: 155946839 - 155991263 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ARHGEF2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001162383.1	NP_001155855.1	19 - 20	2375		86
	NM_001162384.1	NP_001155856.1	19 - 20	2372		86
	NM_004723.3	NP_004714.2	19 - 20	2300		86
	XM_005245587.2	XP_005245644.1	19 - 20	2428		86
	XM_005245588.2	XP_005245645.1	19 - 20	2425		86
	XM_005245589.4	XP_005245646.1	19 - 20	2581		86
	XM_005245590.3	XP_005245647.1	19 - 20	2303		86
	XM_005245591.3	XP_005245648.1	20 - 21	2419		86
	XM_005245592.2	XP_005245649.1	19 - 20	2572		86
	XM_005245593.4	XP_005245650.1	19 - 20	2303		86
	XM_005245594.2	XP_005245651.1	19 - 20	3289		86
	XM_006711622.3	XP_006711685.1	19 - 20	3566		86
	XM_006711623.3	XP_006711686.1	18 - 19	2302		86
	XM_006711624.3	XP_006711687.1	18 - 19	2329		86
	XM_006711625.3	XP_006711688.1	18 - 19	2235		86
	XM_006711626.2	XP_006711689.1	18 - 19	3221		86
	XM_011510136.2	XP_011508438.2	23 - 24	2984		86
	XM_011510137.2	XP_011508439.2	23 - 24	2987		86
	XM_011510139.2	XP_011508441.1	23 - 24	2987		86
	XM_011510141.2	XP_011508443.1	19 - 20	3105		86
	XM_011510143.2	XP_011508445.1	15 - 16	1851		86
	XM_017002794.1	XP_016858283.1	23 - 24	2984		86
	XM_017002795.1	XP_016858284.1	19 - 20	2319		86
	XM_017002796.1	XP_016858285.1	19 - 20	3563		86
	XM_017002797.1	XP_016858286.1	19 - 20	2303		86
	XM_017002798.1	XP_016858287.1	18 - 19	3498		86
	XM_017002799.1	XP_016858288.1	18 - 19	2299		86
GenBank mRNA	AB014551.3	-	23 - 24	2643		86
	AF486838.1	-	19 - 20	2254		86
	AL512715.1	-	19 - 20	2285		86
	BC020567.1	-	19 - 20	2357	4157775	86
	BT007407.1	-	18 - 19	2176		86
	U72206.1	-	19 - 20	2359		86
	X15610.1	-	5 - 6	367		86

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0100018507.hg.1
This assay targets the same location as HTA transcript cluster(s) TC01003328.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ARHGEF2

Gene Ontology Categories:

Process(es)

establishment of mitotic spindle orientation
cell morphogenesis
intracellular protein transport
actin filament organization
negative regulation of microtubule depolymerization
mitotic nuclear division
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
regulation of Rho protein signal transduction
intracellular signal transduction
regulation of cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of transcription from RNA polymerase II promoter
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of neurogenesis
regulation of small GTPase mediated signal transduction
positive regulation of NF-kappaB transcription factor activity
cell division
negative regulation of necroptotic process
cellular response to muramyl dipeptide
cellular response to tumor necrosis factor
cellular hyperosmotic response
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
protein binding
microtubule binding
transcription factor binding
zinc ion binding
Rho GTPase binding
Rac guanyl-nucleotide exchange factor activity
Rac GTPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	TC01003328.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	ENST00000313667.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	ENST00000313695.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	ENST00000361247.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	ENST00000368315.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	ENST00000368316.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	NM_001162383.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	NM_001162384.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR01051756.hg.1	NM_004723.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000313667.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000313695.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000361247.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000368315.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000470541.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	NM_001162383.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	NM_001162384.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	NM_004723.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000313667.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000313695.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000361247.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000368315.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	ENST00000470541.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	NM_001162383.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	NM_001162384.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	NM_004723.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100243546.hg.1	TC0100018507.hg.1	Clariom D TC