Hs01066931_m1

• Gene Symbol: MDM2
• Gene Name: MDM2 proto-oncogene
• Gene Aliases: ACTFS, HDMX, hdm2
• Chromosome Location: Chr.12: 68808149 - 68845544 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MDM2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001145337.2	NP_001138809.1	3 - 4	218		160
	NM_001145339.2	NP_001138811.1	3 - 4	468		160
	NM_002392.5	NP_002383.2	3 - 4	468		160
	XM_005268872.4	XP_005268929.1	3 - 4	396		160
GenBank mRNA	AF092843.1	-	3 - 4	176		160
	AF092844.1	-	3 - 4	176		160
	AF385323.1	-	2 - 3	144		160
	AJ430612.1	-	2 - 3	144		160
	AJ430614.1	-	2 - 3	144		160
	AJ491698.1	-	2 - 3	144		160
	AK290341.1	-	3 - 4	418		160
	AM902646.1	-	2 - 3	144		160
	AM902650.1	-	2 - 3	144		160
	AM902651.1	-	2 - 3	144		160
	AM902654.1	-	2 - 3	144		160
	AM902655.1	-	2 - 3	144		160
	AM902659.1	-	2 - 3	144		160
	AM902666.1	-	2 - 3	144		160
	AM902667.1	-	2 - 3	144		160
	AM902668.1	-	2 - 3	144		160
	AM902669.1	-	2 - 3	144		160
	AM902672.1	-	2 - 3	144		160
	AM902680.1	-	2 - 3	144		160
	AM902681.1	-	2 - 3	144		160
	BC152384.1	-	2 - 3	147		160
	BC152390.1	-	2 - 3	147		160
	BT007258.1	-	2 - 3	144		160
	EU076747.1	-	3 - 4	218		160
	EU076749.1	-	3 - 4	218		160
	HM213901.1	-	2 - 3	144		160
	JX015390.1	-	2 - 3	144		160
	JX015392.1	-	2 - 3	144		160
	M92424.1	-	3 - 4	455		160
	Z12020.1	-	3 - 4	455		160

More Information

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MDM2

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
blood vessel remodeling
regulation of heart rate
atrioventricular valve morphogenesis
endocardial cushion morphogenesis
ventricular septum development
atrial septum development
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
positive regulation of cell proliferation
response to toxic substance
response to carbohydrate
response to iron ion
positive regulation of gene expression
negative regulation of protein processing
viral process
protein ubiquitination
protein sumoylation
peptidyl-lysine modification
protein destabilization
response to magnesium ion
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
response to cocaine
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to morphine
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
response to ether
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
response to antibiotic
positive regulation of protein export from nucleus
response to steroid hormone
cardiac septum morphogenesis
cellular response to hydrogen peroxide
negative regulation of cell cycle arrest
cellular response to antibiotic
cellular response to vitamin B1
cellular response to alkaloid
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to estrogen stimulus
cellular response to hypoxia
cellular response to UV-C
regulation of signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
ubiquitin protein ligase activity
scaffold protein binding