Hs01071439_m1

• Gene Symbol: ROCK2
• Gene Name: Rho associated coiled-coil containing protein kinase 2
• Gene Aliases: ROCK-II
• Chromosome Location: Chr.2: 11179759 - 11345407 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ROCK2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001321643.1	NP_001308572.1	21 - 22	2610		110
	NM_004850.4	NP_004841.2	21 - 22	3066		110
	XM_005246190.3	XP_005246247.1	21 - 22	3100		110
	XM_011510417.2	XP_011508719.1	21 - 22	2565		110
	XM_017005378.1	XP_016860867.1	21 - 22	3097		110
	XM_017005379.1	XP_016860868.1	21 - 22	2495		110
GenBank mRNA	AB014519.1	-	21 - 22	3071		110
	AK299296.1	-	7 - 8	1073		110
	AK310358.1	-	17 - 18	2361		110
	BC111801.1	-	8 - 9	1173	40069866	110
	D87931.1	-	21 - 22	2617		110

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0200011745.hg.1
This assay targets the same location as HTA transcript cluster(s) TC02001576.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ROCK2

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

cytokinesis
positive regulation of protein phosphorylation
protein phosphorylation
smooth muscle contraction
I-kappaB kinase/NF-kappaB signaling
Rho protein signal transduction
positive regulation of endothelial cell migration
positive regulation of gene expression
positive regulation of centrosome duplication
negative regulation of angiogenesis
regulation of cell adhesion
cortical actin cytoskeleton organization
regulation of actin cytoskeleton organization
negative regulation of myosin-light-chain-phosphatase activity
regulation of circadian rhythm
regulation of keratinocyte differentiation
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
rhythmic process
centrosome duplication
regulation of stress fiber assembly
regulation of focal adhesion assembly
cellular response to testosterone stimulus
establishment of protein localization to plasma membrane
regulation of establishment of endothelial barrier
negative regulation of bicellular tight junction assembly
regulation of establishment of cell polarity
regulation of cell motility

Function(s)

protein serine/threonine kinase activity
structural molecule activity
protein binding
ATP binding
Rho GTPase binding
poly(A) RNA binding
metal ion binding
Rho-dependent protein serine/threonine kinase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR02025444.hg.1	TC02001576.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR02025444.hg.1	ENST00000315872.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02025444.hg.1	ENST00000399089.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02025444.hg.1	ENST00000401753.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02025444.hg.1	NM_004850.4	Refseq
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	ENST00000315872.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	ENST00000401753.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	ENST00000616279.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	NM_004850.4	Refseq
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	ENST00000315872.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	ENST00000401753.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	ENST00000616279.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	NM_004850.4	Refseq
Affymetrix Human Clariom D Assay	PSR0200185385.hg.1	TC0200011745.hg.1	Clariom D TC