Hs01071754_m1

• Gene Symbol: XDH
• Gene Name: xanthine dehydrogenase
• Gene Aliases: XO, XOR
• Chromosome Location: Chr.2: 31334320 - 31414777 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: XDH
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000379.3	NP_000370.2	24 - 25	2716		92
	XM_011533095.2	XP_011531397.1	24 - 25	2745		92
	XM_011533096.2	XP_011531398.1	24 - 25	2747		92
GenBank mRNA	D11456.2	-	24 - 25	2694		92
	U06117.1	-	24 - 25	2700		92
	U39487.1	-	24 - 25	2671		92

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0200012163.hg.1
This assay targets the same location as HTA transcript cluster(s) TC02001714.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene XDH

Panther Classification:

Molecular Function -

oxidoreductase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

negative regulation of protein phosphorylation
negative regulation of endothelial cell proliferation
purine nucleotide catabolic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
lactation
xanthine catabolic process
negative regulation of gene expression
negative regulation of endothelial cell differentiation
negative regulation of protein kinase B signaling
oxidation-reduction process
positive regulation of p38MAPK cascade
negative regulation of vascular endothelial growth factor signaling pathway
positive regulation of reactive oxygen species metabolic process
negative regulation of vasculogenesis

Function(s)

xanthine dehydrogenase activity
xanthine oxidase activity
iron ion binding
electron carrier activity
oxidoreductase activity, acting on CH-OH group of donors
oxidoreductase activity, acting on the aldehyde or oxo group of donors
protein homodimerization activity
molybdopterin cofactor binding
flavin adenine dinucleotide binding
2 iron, 2 sulfur cluster binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR02027641.hg.1	TC02001714.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR02027641.hg.1	ENST00000379416.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02027641.hg.1	NM_000379.3	Refseq
Affymetrix Human Clariom D Assay	PSR0200188784.hg.1	ENST00000379416.3	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188784.hg.1	NM_000379.3	Refseq
Affymetrix Human Clariom D Assay	PSR0200188784.hg.1	ENST00000379416.3	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188784.hg.1	NM_000379.3	Refseq
Affymetrix Human Clariom D Assay	PSR0200188784.hg.1	TC0200012163.hg.1	Clariom D TC