Hs01076146_m1

• Gene Symbol: DIS3
• Gene Name: DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease
• Gene Aliases: 2810028N01Rik, EXOSC11, KIAA1008, RRP44, dis3p
• Chromosome Location: Chr.13: 72755402 - 72782128 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DIS3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001128226.2	NP_001121698.1	13 - 14			132
	NM_001322348.1	NP_001309277.1	12 - 13			132
	NM_001322349.1	NP_001309278.1	14 - 15			132
	NM_014953.4	NP_055768.3	13 - 14			132
GenBank mRNA	AB001743.1	-	13 - 14	1782		132
	AB023225.1	-	13 - 14	1758		132
	AF330044.1	-	13 - 14	1791		132
	AK025634.1	-	11 - 12	1361		132
	AK314715.1	-	13 - 14	1867		132
	AL080158.1	-	7 - 8			132
	AL832266.1	-	13 - 14	1844		132
	BC038101.1	-	14 - 15	2090	4827328	132
	BC056143.1	-	13 - 14	1856	5505671	132

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1300009232.hg.1
This assay targets the same location as HTA transcript cluster(s) TC13000727.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene DIS3

Panther Classification:

Molecular Function -

exoribonuclease

Gene Ontology Categories:

Process(es)

rRNA processing
mRNA catabolic process
rRNA catabolic process
regulation of mRNA stability
positive regulation of GTPase activity
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
CUT catabolic process
RNA phosphodiester bond hydrolysis, exonucleolytic

Function(s)

3'-5'-exoribonuclease activity
RNA binding
endonuclease activity
guanyl-nucleotide exchange factor activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR13008376.hg.1	ENST00000377767.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13008376.hg.1	ENST00000377780.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13008376.hg.1	ENST00000545453.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13008376.hg.1	NM_001128226.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR13008376.hg.1	NM_014953.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR13008376.hg.1	TC13000727.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000377767.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000377780.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000490646.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000545453.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	NM_001128226.2	Refseq
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	NM_014953.4	Refseq
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000377767.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000377780.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000490646.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	ENST00000545453.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	NM_001128226.2	Refseq
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	NM_014953.4	Refseq
Affymetrix Human Clariom D Assay	PSR1300162052.hg.1	TC1300009232.hg.1	Clariom D TC