Hs01078136_m1 Best Coverage

• Gene Symbol: JAK2
• Gene Name: Janus kinase 2
• Gene Aliases: JTK10, THCYT3
• Chromosome Location: Chr.9: 4985086 - 5128183 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: JAK2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001322194.1	NP_001309123.1	8 - 9	1652		84
	NM_001322195.1	NP_001309124.1	7 - 8	1170		84
	NM_001322196.1	NP_001309125.1	7 - 8	1483		84
	NM_001322198.1	NP_001309127.1	8 - 9	1471		84
	NM_001322199.1	NP_001309128.1	8 - 9	1413		84
	NM_001322204.1	NP_001309133.1	5 - 6	922		84
	NM_004972.3	NP_004963.1	8 - 9	1551		84
GenBank mRNA	AF001362.1	-	6 - 7	1057		84
	AF005216.1	-	8 - 9	1551		84
	AF058925.1	-	8 - 9	1534		84
	AK292525.1	-	7 - 8	1170		84
	AK302618.1	-	5 - 6	981		84
	AY973034.1	-	7 - 8	1128		84
	BC039695.1	-	7 - 8	1155	5556026	84

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0900006538.hg.1
This assay targets the same location as HTA transcript cluster(s) TC09000035.hg.1

Additional Information:

This assay is in the 5'UTR region of the NM_001322198.1,NM_001322199.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Protein Kinase, Mammalian Gene Collection, Recommended Assay, Homo sapiens, Human PDGF Pathway, Human Erythropoietin Pathway, Human iNOS Signaling, Human EGF Pathway, Human Interferon Pathway, HUMAN JAK-STAT PATHWAY, HUMAN IL-3 PATHWAY, HUMAN PI3K SIGNALING, HUMAN PANCREATIC ADENOCARCINOMA, Inventoried, Human_EGF_Pathway, Human_PDGF_Pathway, Human_Interferon_Pathway, Human_iNOS_Signaling, Human_Erythropoietin_Pathway, Human_Pancreatic_Adenocarcinoma, Human_IL-3_Pathway, Human_PI3K_Signaling, Human_JAK-STAT_Pathway, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene JAK2

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
adaptive immune response
protein phosphorylation
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
movement of cell or subcellular component
signal transduction
enzyme linked receptor protein signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
JAK-STAT cascade
tyrosine phosphorylation of STAT protein
STAT protein import into nucleus
mesoderm development
blood coagulation
positive regulation of cell proliferation
negative regulation of cell proliferation
intrinsic apoptotic signaling pathway in response to oxidative stress
negative regulation of cardiac muscle cell apoptotic process
positive regulation of cell-substrate adhesion
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
negative regulation of cell-cell adhesion
actin filament polymerization
cell differentiation
erythrocyte differentiation
positive regulation of cell migration
axon regeneration
mineralocorticoid receptor signaling pathway
positive regulation of insulin secretion
response to lipopolysaccharide
positive regulation of phosphoprotein phosphatase activity
positive regulation of interleukin-1 beta production
positive regulation of tumor necrosis factor production
positive regulation of protein import into nucleus, translocation
response to hydroperoxide
tumor necrosis factor-mediated signaling pathway
response to tumor necrosis factor
histone H3-Y41 phosphorylation
intracellular signal transduction
interleukin-12-mediated signaling pathway
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
tyrosine phosphorylation of Stat3 protein
tyrosine phosphorylation of Stat5 protein
tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
activation of JAK2 kinase activity
regulation of apoptotic process
positive regulation of DNA binding
negative regulation of DNA binding
negative regulation of neuron apoptotic process
positive regulation of GTPase activity
innate immune response
positive regulation of nitric oxide biosynthetic process
positive regulation of cell differentiation
negative regulation of heart contraction
response to antibiotic
protein autophosphorylation
platelet-derived growth factor receptor signaling pathway
regulation of inflammatory response
positive regulation of inflammatory response
positive regulation of peptidyl-tyrosine phosphorylation
positive regulation of cell activation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of nitric-oxide synthase biosynthetic process
interferon-gamma-mediated signaling pathway
regulation of interferon-gamma-mediated signaling pathway
growth hormone receptor signaling pathway
JAK-STAT cascade involved in growth hormone signaling pathway
positive regulation of growth hormone receptor signaling pathway
mammary gland epithelium development
response to interleukin-12
extrinsic apoptotic signaling pathway
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Function(s)

protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
growth hormone receptor binding
interleukin-12 receptor binding
protein binding
ATP binding
protein C-terminus binding
protein kinase binding
heme binding
type 1 angiotensin receptor binding
acetylcholine receptor binding
histone kinase activity (H3-Y41 specific)
SH2 domain binding
histone binding
phosphatidylinositol 3-kinase binding
insulin receptor substrate binding
metal ion binding
peptide hormone receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR09000443.hg.1	TC09000035.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR09000443.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09000443.hg.1	ENST00000539801.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09000443.hg.1	ENST00000544510.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09000443.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000442675.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000442675.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000442675.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000442675.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000476574.5	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	ENST00000487310.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	TC0900006538.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900144827.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	PSR0900144827.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900144827.hg.1	ENST00000381652.3	Ensembl
Affymetrix Human Clariom D Assay	PSR0900144827.hg.1	NM_004972.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900144827.hg.1	TC0900006538.hg.1	Clariom D TC