Hs01099685_m1

• Gene Symbol: ISL1
• Gene Name: ISL LIM homeobox 1
• Gene Aliases: ISLET1, Isl-1
• Chromosome Location: Chr.5: 51383124 - 51394730 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ISL1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002202.2	NP_002193.2	2 - 3	766		76
GenBank mRNA	AK290742.1	-	2 - 3	484		76
	BC031213.1	-	2 - 3	767	5269369	76
	S70721.1	-	2 - 3	223		76
	U07559.1	-	2 - 3	457		76

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0500007349.hg.1
This assay targets the same location as HTA transcript cluster(s) TC05000212.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ISL1

Gene Ontology Categories:

Process(es)

negative regulation of transcription by RNA polymerase II
neural crest cell migration
secondary heart field specification
outflow tract septum morphogenesis
outflow tract morphogenesis
endocardial cushion morphogenesis
cardiac right ventricle morphogenesis
regulation of secondary heart field cardioblast proliferation
regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
positive regulation of cell population proliferation
positive regulation of vascular endothelial growth factor production
spinal cord motor neuron cell fate specification
spinal cord motor neuron differentiation
visceral motor neuron differentiation
trigeminal nerve development
pituitary gland development
pancreas development
axon regeneration
retinal ganglion cell axon guidance
positive regulation of insulin secretion
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-1 alpha production
positive regulation of interleukin-1 beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
negative regulation of intracellular estrogen receptor signaling pathway
positive regulation of histone acetylation
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of DNA binding
negative regulation of neuron apoptotic process
negative regulation of neuron differentiation
positive regulation of angiogenesis
positive regulation of transcription by RNA polymerase II
neuron fate specification
mesenchymal cell differentiation
sensory system development
peripheral nervous system neuron axonogenesis
negative regulation of inflammatory response
ventricular cardiac muscle tissue morphogenesis
pharyngeal system development
cardiac muscle cell myoblast differentiation
innervation
atrial septum morphogenesis
cardiac cell fate determination
cellular response to glucocorticoid stimulus
positive regulation of granulocyte colony-stimulating factor production
negative regulation of protein homodimerization activity
negative regulation of canonical Wnt signaling pathway
positive regulation of macrophage colony-stimulating factor production

Function(s)

RNA polymerase II cis-regulatory region sequence-specific DNA binding
chromatin binding
transcription coactivator activity
protein binding
zinc ion binding
nuclear receptor binding
estrogen receptor binding
bHLH transcription factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05002583.hg.1	ENST00000230658.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002583.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05002583.hg.1	TC05000212.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05002584.hg.1	ENST00000230658.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002584.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05002584.hg.1	TC05000212.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05002582.hg.1	ENST00000230658.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002582.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05002582.hg.1	TC05000212.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05002585.hg.1	ENST00000230658.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002585.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002585.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05002585.hg.1	TC05000212.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05002586.hg.1	ENST00000230658.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002586.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002586.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05002586.hg.1	TC05000212.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05002589.hg.1	ENST00000230658.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002589.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002589.hg.1	NM_002202.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05002589.hg.1	TC05000212.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR0500149644.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149644.hg.1	TC0500007349.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0500149644.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	TC0500007349.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	TC0500007349.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	ENST00000505475.3	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149649.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149647.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149647.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149647.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149647.hg.1	TC0500007349.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0500149647.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149647.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149647.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149646.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149646.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149646.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149646.hg.1	TC0500007349.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0500149646.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149646.hg.1	ENST00000511384.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149646.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149645.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149645.hg.1	NM_002202.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500149645.hg.1	TC0500007349.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0500149645.hg.1	ENST00000230658.11	Ensembl
Affymetrix Human Clariom D Assay	PSR0500149645.hg.1	NM_002202.2	Refseq