Hs01108399_g1

• Gene Symbol: NR1H3
• Gene Name: nuclear receptor subfamily 1 group H member 3
• Gene Aliases: LXR-a, LXRA, RLD-1
• Chromosome Location: Chr.11: 47248300 - 47269033 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: NR1H3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_005252709.1	XP_005252766.1	3 - 4	244		62
	XM_005252710.1	XP_005252767.1	2 - 3	142		62
	XM_006718115.1	XP_006718178.1	2 - 3	250		62

More Information

Additional Information:

This assay is in the 5'UTR region of the XM_005252709.1, XM_005252710.1, XM_006718115.1 transcripts.

• Set Membership: Amplicon length less than or equal to 70, Detect Genomic DNA, Homo sapiens, Probe spans exons

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
negative regulation of macrophage derived foam cell differentiation
positive regulation of triglyceride biosynthetic process
positive regulation of receptor biosynthetic process
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
intracellular receptor signaling pathway
positive regulation of cellular protein metabolic process
negative regulation of lipid transport
positive regulation of cholesterol transport
response to progesterone
positive regulation of toll-like receptor 4 signaling pathway
cholesterol homeostasis
regulation of circadian rhythm
negative regulation of macrophage activation
apoptotic cell clearance
steroid hormone mediated signaling pathway
positive regulation of fatty acid biosynthetic process
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of pinocytosis
negative regulation of inflammatory response
positive regulation of lipoprotein lipase activity
lipid homeostasis
sterol homeostasis
negative regulation of interferon-gamma-mediated signaling pathway
triglyceride homeostasis
cellular response to lipopolysaccharide
negative regulation of pancreatic juice secretion
negative regulation of secretion of lysosomal enzymes
regulation of cholesterol homeostasis
positive regulation of cholesterol homeostasis

Function(s)

DNA binding
steroid hormone receptor activity
transcription coactivator activity
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
zinc ion binding
cholesterol binding
sterol response element binding
sequence-specific DNA binding
transcription regulatory region DNA binding