Hs01112310_m1

• Gene Symbol: ATM
• Gene Name: ATM serine/threonine kinase
• Gene Aliases: AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1
• Chromosome Location: Chr.11: 108222484 - 108369102 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ATM
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000051.3	NP_000042.3	45 - 46	6954		104
	XM_005271561.4	XP_005271618.2	46 - 47	7015		104
	XM_005271562.4	XP_005271619.2	45 - 46	7088		104
	XM_006718843.3	XP_006718906.1	45 - 46	6721		104
	XM_006718845.1	XP_006718908.1	20 - 21	2594		104
	XM_011542840.2	XP_011541142.1	46 - 47	6809		104
	XM_011542842.2	XP_011541144.1	44 - 45	6763		104
	XM_011542843.2	XP_011541145.1	45 - 46	7302		104
	XM_011542844.2	XP_011541146.1	45 - 46	6904		104
	XM_011542845.1	XP_011541147.1	37 - 38	5417		104
	XM_017017789.1	XP_016873278.1	46 - 47	7512		104
	XM_017017790.1	XP_016873279.1	45 - 46	6909		104
GenBank mRNA	AK299843.1	-	7 - 8	785		104
	BC137169.1	-	19 - 20	2592	9021166	104
	CR749436.1	-		1973		104
	U26455.1	-	19 - 20	2784		104
	U33841.1	-	46 - 47	6758		104

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1100008985.hg.1
This assay targets the same location as HTA transcript cluster(s) TC11000980.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Protein Kinase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ATM

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
response to hypoxia
somitogenesis
pre-B cell allelic exclusion
DNA replication
DNA repair
double-strand break repair via nonhomologous end joining
protein phosphorylation
cellular response to DNA damage stimulus
DNA damage induced protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
telomere maintenance via telomerase
cell cycle arrest
mitotic spindle assembly checkpoint
reciprocal meiotic recombination
signal transduction
brain development
heart development
determination of adult lifespan
intrinsic apoptotic signaling pathway in response to DNA damage
response to ionizing radiation
regulation of autophagy
histone phosphorylation
peptidyl-serine phosphorylation
negative regulation of B cell proliferation
positive regulation of telomere maintenance via telomerase
positive regulation of histone phosphorylation
V(D)J recombination
phosphatidylinositol-3-phosphate biosynthetic process
peptidyl-serine autophosphorylation
lipoprotein catabolic process
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of neuron apoptotic process
meiotic telomere clustering
protein autophosphorylation
oocyte development
neuron apoptotic process
regulation of telomerase activity
histone mRNA catabolic process
cellular response to gamma radiation
cellular response to X-ray
cellular response to nitrosative stress
signal transduction involved in mitotic G2 DNA damage checkpoint
replicative senescence
establishment of RNA localization to telomere
establishment of macromolecular complex localization to telomere
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
negative regulation of TORC1 signaling
negative regulation of telomere capping
positive regulation of telomere maintenance via telomere lengthening
positive regulation of telomerase catalytic core complex assembly

Function(s)

DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
protein complex binding
protein dimerization activity
protein N-terminus binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR11012232.hg.1	ENST00000278616.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11012232.hg.1	ENST00000452508.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11012232.hg.1	NM_000051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11012232.hg.1	TC11000980.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000278616.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000452508.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000524792.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000533690.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	NM_000051.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000278616.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000452508.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000524792.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	ENST00000533690.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	NM_000051.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100166417.hg.1	TC1100008985.hg.1	Clariom D TC