Hs01122246_m1

• Gene Symbol: DAB2
• Gene Name: DAB2, clathrin adaptor protein
• Gene Aliases: DOC-2, DOC2
• Chromosome Location: Chr.5: 39371674 - 39425233 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DAB2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001244871.1	NP_001231800.1	6 - 7	1079		122
	NM_001343.3	NP_001334.2	6 - 7	1079		122
GenBank mRNA	AF188298.1	-	5 - 6	636		122
	AK297984.1	-	2 - 3	193		122
	AK314381.1	-	6 - 7	827		122
	BC003064.2	-	6 - 7	675	3504380	122
	L16886.1	-	4 - 5	419		122
	U39050.1	-	5 - 6	647		122
	U53446.1	-	6 - 7	692		122

More Information

Additional Information:

This assay is in the 5'UTR region of the AK297984.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene DAB2

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
receptor-mediated endocytosis
apoptotic process
integrin-mediated signaling pathway
multicellular organism development
cell proliferation
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
protein transport
Wnt signaling pathway
positive regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
leading edge cell differentiation
negative regulation of apoptotic process
positive regulation of endocytosis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of SMAD protein import into nucleus
negative regulation of androgen receptor signaling pathway
negative regulation of canonical Wnt signaling pathway
negative regulation of protein localization to plasma membrane
positive regulation of Wnt signaling pathway, planar cell polarity pathway
positive regulation of clathrin-mediated endocytosis
positive regulation of early endosome to late endosome transport

Function(s)

protein binding
protein C-terminus binding
clathrin adaptor activity
cargo receptor activity
SMAD binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	TC05003425.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	ENST00000320816.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	ENST00000339788.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	ENST00000509337.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	ENST00000512525.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	ENST00000545653.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	NM_001244871.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05018228.hg.1	NM_001343.3	Refseq