Hs01128470_g1

• Gene Symbol: DOCK2
• Gene Name: dedicator of cytokinesis 2
• Gene Aliases: IMD40
• Chromosome Location: Chr.5: 169637247 - 170083382 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DOCK2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_004946.2	NP_004937.1	31 - 32	3259		77
GenBank mRNA	AK128107.1	-	17 - 18	1820		77
	BC104900.1	-	31 - 32	3215	8143903	77
	BC113457.1	-	31 - 32	3215	8322509	77
	BC143358.1	-	32 - 33	3266		77
	D86964.1	-	31 - 32	3217		77

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0500009378.hg.1
This assay targets the same location as HTA transcript cluster(s) TC05000929.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene DOCK2

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

membrane raft polarization
establishment of T cell polarity
immunological synapse formation
myeloid dendritic cell activation involved in immune response
chemotaxis
small GTPase mediated signal transduction
actin cytoskeleton organization
positive regulation of GTPase activity
macropinocytosis
positive thymic T cell selection
negative thymic T cell selection
alpha-beta T cell proliferation
regulation of defense response to virus by virus
positive regulation of phagocytosis

Function(s)

GTPase activator activity
protein binding
Rac guanyl-nucleotide exchange factor activity
T cell receptor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05013520.hg.1	TC05000929.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05013520.hg.1	ENST00000256935.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05013520.hg.1	ENST00000520908.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05013520.hg.1	ENST00000523351.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05013520.hg.1	ENST00000540750.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05013520.hg.1	NM_004946.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000256935.12	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000520908.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000523351.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000524185.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	NM_004946.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000256935.12	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000520908.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000523351.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	ENST00000524185.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	NM_004946.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500165718.hg.1	TC0500009378.hg.1	Clariom D TC