Hs01549949_m1

• Gene Symbol: FN1
• Gene Name: fibronectin 1
• Gene Aliases: CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF
• Chromosome Location: Chr.2: 215360440 - 215436167 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: FN1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001306129.1	NP_001293058.1	21 - 22	3613		58
	NM_001306130.1	NP_001293059.1	21 - 22	3613		58
	NM_001306131.1	NP_001293060.1	21 - 22	3613		58
	NM_001306132.1	NP_001293061.1	21 - 22	3613		58
	NM_002026.3	NP_002017.1	21 - 22	3611		58
	NM_212474.2	NP_997639.1	21 - 22	3611		58
	NM_212476.2	NP_997641.1	21 - 22	3611		58
	NM_212478.2	NP_997643.1	21 - 22	3611		58
	NM_212482.2	NP_997647.1	21 - 22	3611		58
	XM_005246397.1	XP_005246454.1	21 - 22	3710		58
	XM_005246398.1	XP_005246455.1	21 - 22	3710		58
	XM_005246399.1	XP_005246456.1	21 - 22	3710		58
	XM_005246401.1	XP_005246458.1	21 - 22	3710		58
	XM_005246402.1	XP_005246459.1	21 - 22	3710		58
	XM_005246403.1	XP_005246460.1	21 - 22	3710		58
	XM_005246404.1	XP_005246461.1	21 - 22	3710		58
	XM_005246405.1	XP_005246462.1	21 - 22	3710		58
	XM_005246406.1	XP_005246463.1	21 - 22	3710		58
	XM_005246407.1	XP_005246464.1	21 - 22	3710		58
	XM_005246408.1	XP_005246465.1	21 - 22	3710		58
	XM_005246409.1	XP_005246466.1	21 - 22	3710		58
	XM_005246410.1	XP_005246467.1	21 - 22	3710		58
	XM_005246411.1	XP_005246468.1	21 - 22	3710		58
	XM_005246412.1	XP_005246469.1	21 - 22	3710		58
	XM_005246414.1	XP_005246471.1	21 - 22	3710		58
	XM_005246416.1	XP_005246473.1	21 - 22	3710		58
	XM_017003692.1	XP_016859181.1	21 - 22	3710		58
	XM_017003693.1	XP_016859182.1	21 - 22	3710		58
	XM_017003694.1	XP_016859183.1	21 - 22	3710		58
	XM_017003695.1	XP_016859184.1	21 - 22	3710		58
GenBank mRNA	AB191261.1	-	21 - 22	3611		58
	AB209840.1	-	21 - 22	3603		58
	AL832202.1	-	21 - 22	3612		58
	AL832771.1	-	21 - 22	3612		58
	BC117176.1	-	21 - 22	3591	40125727	58
	BC143754.1	-	21 - 22	3591	9052268	58
	BC143763.1	-	21 - 22	3591	9052277	58
	BX537590.1	-	21 - 22	3612		58
	BX538017.1	-	21 - 22	3612		58
	BX538018.1	-	21 - 22	3612		58
	BX640608.1	-	21 - 22	3611		58
	BX640731.1	-	21 - 22	3612		58
	BX640802.1	-	21 - 22	3613		58
	BX640803.1	-	21 - 22	3611		58
	BX640875.1	-	21 - 22	3612		58
	BX640920.1	-	1 - 2	47		58
	BX640999.1	-	16 - 17	2587		58
	BX649182.1	-	21 - 22	3613		58
	CR749281.1	-	21 - 22	3650		58
	CR749316.1	-	21 - 22	3610		58
	CR749317.1	-	21 - 22	3610		58
	CR749666.1	-	1 - 2	226		58
	X02761.1	-	21 - 22	3265		58

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0200015650.hg.1
This assay targets the same location as HTA transcript cluster(s) TC02002747.hg.1

Additional Information:

This assay is in the 5'UTR region of the CR749666.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene FN1

Panther Classification:

Molecular Function -

extracellular matrix structural protein

Gene Ontology Categories:

Process(es)

angiogenesis
cell activation
regulation of protein phosphorylation
platelet degranulation
response to ischemia
acute-phase response
cell-substrate junction assembly
cell adhesion
calcium-independent cell-matrix adhesion
positive regulation of cell proliferation
glial cell migration
regulation of cell shape
response to wounding
response to ozone
positive regulation of gene expression
positive regulation of peptidase activity
peptide cross-linking
extracellular matrix disassembly
extracellular matrix organization
integrin activation
substrate adhesion-dependent cell spreading
cellular response to vascular endothelial growth factor stimulus
endodermal cell differentiation
cellular response to platelet-derived growth factor stimulus
wound healing
negative regulation of apoptotic process
positive regulation of axon extension
positive regulation of fibroblast proliferation
leukocyte migration
positive regulation of chemotaxis
response to glucocorticoid
regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to mercury ion
cellular response to glucose stimulus
cellular response to interleukin-1
cellular response to prostaglandin E stimulus
cellular response to transforming growth factor beta stimulus
cellular response to BMP stimulus
positive regulation of substrate-dependent cell migration, cell attachment to substrate
negative regulation of transforming growth factor-beta secretion

Function(s)

protease binding
integrin binding
protein binding
collagen binding
heparin binding
peptidase activator activity
identical protein binding
mercury ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	TC02002747.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000265313.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000323926.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000336916.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000345488.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000346544.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000354785.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000356005.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000357009.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000357867.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000359671.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000421182.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000432072.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000443816.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	ENST00000446046.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	NM_002026.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	NM_212474.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	NM_212476.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	NM_212478.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02044172.hg.1	NM_212482.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000323926.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000336916.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000354785.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000356005.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000357867.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000359671.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000421182.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000432072.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000443816.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000446046.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306129.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306130.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306131.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306132.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_002026.3	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212474.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212476.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212478.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212482.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000323926.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000336916.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000354785.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000356005.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000357867.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000359671.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000421182.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000432072.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000443816.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	ENST00000446046.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306129.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306130.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306131.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_001306132.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_002026.3	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212474.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212476.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212478.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	NM_212482.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214869.hg.1	TC0200015650.hg.1	Clariom D TC