Hs01562461_m1

• Gene Symbol: UBR5
• Gene Name: ubiquitin protein ligase E3 component n-recognin 5
• Gene Aliases: DD5, EDD, EDD1, HYD
• Chromosome Location: Chr.8: 102252273 - 102412719 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: UBR5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001282873.1	NP_001269802.1	28 - 29	4118		122
	NM_015902.5	NP_056986.2	28 - 29	4118		122
	XM_005250962.4	XP_005251019.1	7 - 8	879		122
	XM_011517104.2	XP_011515406.2	27 - 28	4103		122
	XM_011517105.2	XP_011515407.2	27 - 28	4103		122
	XM_011517106.2	XP_011515408.2	27 - 28	4085		122
	XM_017013533.1	XP_016869022.1	27 - 28	4103		122
	XM_017013534.1	XP_016869023.1	27 - 28	4103		122
GenBank mRNA	AB020703.3	-	28 - 29	4118		122
	AF006010.2	-	28 - 29	3696		122
	BC137234.1	-	28 - 29	3690	9021231	122
	U95000.1	-	28 - 29	3660		122

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0800011314.hg.1
This assay targets the same location as HTA transcript cluster(s) TC08001497.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene UBR5

Panther Classification:

Molecular Function -

ubiquitin-protein ligase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

protein polyubiquitination
DNA repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
cell proliferation
positive regulation of protein import into nucleus, translocation
positive regulation of catenin import into nucleus
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
progesterone receptor signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of histone H2A K63-linked ubiquitination
negative regulation of double-strand break repair

Function(s)

RNA binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ubiquitin-ubiquitin ligase activity
ubiquitin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR08019664.hg.1	TC08001497.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR08019664.hg.1	ENST00000220959.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR08019664.hg.1	ENST00000520539.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR08019664.hg.1	ENST00000521922.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR08019664.hg.1	NM_015902.5	Refseq
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	ENST00000220959.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	ENST00000520539.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	ENST00000521922.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	NM_001282873.1	Refseq
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	NM_015902.5	Refseq
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	ENST00000220959.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	ENST00000520539.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	ENST00000521922.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	NM_001282873.1	Refseq
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	NM_015902.5	Refseq
Affymetrix Human Clariom D Assay	PSR0800177280.hg.1	TC0800011314.hg.1	Clariom D TC