Hs01567090_m1

• Gene Symbol: FGFR2
• Gene Name: fibroblast growth factor receptor 2
• Gene Aliases: BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
• Chromosome Location: Chr.10: 121478330 - 121598656 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: FGFR2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001144913.1	NP_001138385.1	6 - 7	1088		63
	NM_001144919.1	NP_001138391.1	6 - 7	1318		63
	NM_022970.3	NP_075259.4	7 - 8	1585		63
	NR_073009.1		5 - 6	1240		63
	XM_006717708.2	XP_006717771.1	7 - 8	1783		63
	XM_006717710.3	XP_006717773.1	7 - 8	1783		63
	XM_006717711.2	XP_006717774.1	5 - 6	821		63
	XM_006717712.2	XP_006717775.1	4 - 5	743		63
	XM_017015920.1	XP_016871409.1	7 - 8	1783		63
	XM_017015922.1	XP_016871411.1	5 - 6	821		63
GenBank mRNA	AB030073.1	-	7 - 8	1356		63
	AB030074.1	-	7 - 8	1356		63
	AB030075.1	-	7 - 8	1356		63
	AB030076.1	-	7 - 8	1356		63
	AB030077.1	-	7 - 8	1356		63
	AB030078.1	-	7 - 8	1356		63
	AK026508.1	-	6 - 7	1292		63
	KP192323.1	-	5 - 6	755		63
	KP192324.1	-	5 - 6	755		63
	M80634.1	-	7 - 8	1356		63
	M97193.1	-	7 - 8	1549		63
	U11814.1	-	7 - 8	1196		63
	X56191.1	-	6 - 7	962		63

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1000012050.hg.1
This assay targets the same location as HTA transcript cluster(s) TC10001711.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene FGFR2

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
angiogenesis
ureteric bud development
in utero embryonic development
epithelial to mesenchymal transition
positive regulation of mesenchymal cell proliferation
outflow tract septum morphogenesis
membranous septum morphogenesis
apoptotic process
cell-cell signaling
axonogenesis
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
regulation of smoothened signaling pathway
post-embryonic development
embryonic pattern specification
organ morphogenesis
regulation of cell fate commitment
positive regulation of phospholipase activity
regulation of phosphatidylinositol 3-kinase signaling
morphogenesis of embryonic epithelium
peptidyl-tyrosine phosphorylation
orbitofrontal cortex development
ventricular zone neuroblast division
pyramidal neuron development
gland morphogenesis
positive regulation of Wnt signaling pathway
bone mineralization
lung development
epithelial cell differentiation
midbrain development
otic vesicle formation
hair follicle morphogenesis
lacrimal gland development
regulation of osteoblast proliferation
multicellular organism growth
organ growth
fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow
fibroblast growth factor receptor signaling pathway involved in hemopoiesis
fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow
fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development
phosphatidylinositol-3-phosphate biosynthetic process
regulation of multicellular organism growth
regulation of fibroblast growth factor receptor signaling pathway
inner ear morphogenesis
odontogenesis
positive regulation of MAPK cascade
positive regulation of GTPase activity
cell fate commitment
regulation of osteoblast differentiation
positive regulation of cell cycle
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
lung alveolus development
mesodermal cell differentiation
embryonic digestive tract morphogenesis
embryonic organ morphogenesis
digestive tract development
embryonic organ development
reproductive structure development
positive regulation of smooth muscle cell proliferation
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
epidermis morphogenesis
branching morphogenesis of a nerve
mesenchymal cell differentiation
positive regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
regulation of smooth muscle cell differentiation
positive regulation of cell division
ventricular cardiac muscle tissue morphogenesis
positive regulation of cardiac muscle cell proliferation
limb bud formation
bone development
bone morphogenesis
branching involved in prostate gland morphogenesis
branching involved in salivary gland morphogenesis
bud elongation involved in lung branching
lung lobe morphogenesis
lung-associated mesenchyme development
positive regulation of epithelial cell proliferation involved in lung morphogenesis
prostate gland morphogenesis
prostate epithelial cord elongation
prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
fibroblast growth factor receptor signaling pathway involved in mammary gland specification
lateral sprouting from an epithelium
mammary gland bud formation
epithelial cell proliferation involved in salivary gland morphogenesis
branch elongation involved in salivary gland morphogenesis
branching involved in labyrinthine layer morphogenesis
regulation of branching involved in prostate gland morphogenesis
regulation of morphogenesis of a branching structure
mesenchymal cell differentiation involved in lung development
mesenchymal cell proliferation involved in lung development
regulation of ERK1 and ERK2 cascade
positive regulation of ERK1 and ERK2 cascade
positive regulation of canonical Wnt signaling pathway

Function(s)

protein tyrosine kinase activity
fibroblast growth factor-activated receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
heparin binding
1-phosphatidylinositol-3-kinase activity
fibroblast growth factor binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	ENST00000360144.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	ENST00000369056.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	ENST00000369059.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	ENST00000457416.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	NM_001144913.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	NM_001144919.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	NM_022970.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR10022611.hg.1	TC10001711.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000360144.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000369056.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000369058.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000369059.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000457416.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000463870.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000490349.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000604236.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NM_001144913.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NM_001144919.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NM_022970.3	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NR_073009.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000360144.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000369056.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000369058.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000369059.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000457416.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000463870.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000490349.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	ENST00000604236.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NM_001144913.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NM_001144919.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NM_022970.3	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	NR_073009.1	Refseq
Affymetrix Human Clariom D Assay	PSR1000182419.hg.1	TC1000012050.hg.1	Clariom D TC