Hs01568112_m1

• Gene Symbol: TNFAIP3
• Gene Name: TNF alpha induced protein 3
• Gene Aliases: A20, AISBL, OTUD7C, TNFA1P2
• Chromosome Location: Chr.6: 137866317 - 137883314 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TNFAIP3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001270507.1	NP_001257436.1	1 - 2	327		69
	NM_001270508.1	NP_001257437.1	1 - 2	351		93
	XM_011536096.1	XP_011534398.1	1 - 2	331		93
GenBank mRNA	DB143089.1	-	1 - 2	297		69
	HY009939.1	-	1 - 2	409		93

More Information

Additional Information:

This assay is in the 5'UTR region of the NM_001270507.1, NM_001270508.1, XM_011536096.1 transcripts.

• Set Membership: Amplicon length less than or equal to 70, Amplicon length between 86 and 100, Apoptosis, Homo sapiens, Probe spans exons

Panther Classification:

Molecular Function -

cysteine protease

Gene Ontology Categories:

Process(es)

B-1 B cell homeostasis
response to molecule of bacterial origin
regulation of germinal center formation
negative regulation of chronic inflammatory response
apoptotic process
inflammatory response
regulation of tumor necrosis factor-mediated signaling pathway
protein deubiquitination
negative regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
negative regulation of type I interferon production
response to muramyl dipeptide
negative regulation of interleukin-1 beta production
negative regulation of interleukin-2 production
negative regulation of interleukin-6 production
negative regulation of tumor necrosis factor production
negative regulation of toll-like receptor 2 signaling pathway
negative regulation of toll-like receptor 3 signaling pathway
negative regulation of toll-like receptor 4 signaling pathway
negative regulation of toll-like receptor 5 signaling pathway
protein K11-linked deubiquitination
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of protein catabolic process
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of bone resorption
negative regulation of innate immune response
negative regulation of smooth muscle cell proliferation
regulation of defense response to virus by host
regulation of inflammatory response
negative regulation of inflammatory response
negative regulation of B cell activation
protein oligomerization
regulation of vascular wound healing
cellular response to hydrogen peroxide
nucleotide-binding oligomerization domain containing signaling pathway
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
protein K63-linked deubiquitination
protein K48-linked ubiquitination
protein K48-linked deubiquitination
cellular response to lipopolysaccharide
protein deubiquitination involved in ubiquitin-dependent protein catabolic process
tolerance induction to lipopolysaccharide
establishment of protein localization to vacuole
negative regulation of osteoclast proliferation
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of cellular protein catabolic process
positive regulation of hepatocyte proliferation
negative regulation of CD40 signaling pathway
negative regulation of endothelial cell apoptotic process

Function(s)

protease binding
DNA binding
ubiquitin-protein transferase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
ligase activity
kinase binding
ubiquitin binding
protein self-association
K63-linked polyubiquitin binding