Hs01568539_m1

• Gene Symbol: TIRAP
• Gene Name: TIR domain containing adaptor protein
• Gene Aliases: BACTS1, Mal, MyD88-2, wyatt
• Chromosome Location: Chr.11: 126281268 - 126294933 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TIRAP
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_148910.2	NP_683708.1	2 - 3	231		80
	XM_017017162.1	XP_016872651.1	2 - 3	252		80
GenBank mRNA	AF378129.1	-	2 - 3	212		80
	AF410783.1	-	2 - 3	208		80

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1100009449.hg.1
This assay targets the same location as HTA transcript cluster(s) TC11001172.hg.1

Additional Information:

This assay is in the 5'UTR region of the AF378129.1,AF410783.1,NM_148910.2,XM_017017162.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TIRAP

Gene Ontology Categories:

Process(es)

MyD88-dependent toll-like receptor signaling pathway
inflammatory response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
myeloid cell differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-15 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor 2 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
toll-like receptor 4 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
TIRAP-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
innate immune response
regulation of innate immune response
positive regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
3'-UTR-mediated mRNA stabilization
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
positive regulation of neutrophil chemotaxis
positive regulation of protein homodimerization activity
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

protein kinase C binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
protein binding, bridging
Toll-like receptor 4 binding
Toll-like receptor 2 binding
protein homodimerization activity
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392678.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392679.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000392680.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000462401.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000462401.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000462401.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000462401.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000462401.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000462401.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000467006.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000467006.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000467006.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000467006.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000467006.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000467006.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000479770.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000479770.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000479770.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000479770.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000479770.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000479770.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	ENST00000488598.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_001039661.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1100009449.hg.1	NM_148910.2	Refseq