Hs01586108_m1

• Gene Symbol: PSEN2
• Gene Name: presenilin 2
• Gene Aliases: AD3L, AD4, CMD1V, PS2, STM2
• Chromosome Location: Chr.1: 226870572 - 226903829 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PSEN2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_012486.2	NP_036618.2	9 - 10	1315		135
	XM_017001836.1	XP_016857325.1	8 - 9	1128		135
GenBank mRNA	AK292299.1	-	10 - 11	1267		135
	U34349.1	-	7 - 8	979		135

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0100011811.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PSEN2

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

response to hypoxia
membrane protein ectodomain proteolysis
calcium ion transport
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
intracellular signal transduction
amyloid precursor protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway
beta-amyloid metabolic process

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000366782.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000366783.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000422240.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000460775.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000471728.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000472139.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000487450.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000626989.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	NM_000447.2	Refseq
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	NM_012486.2	Refseq
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000366782.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000366783.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000422240.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000460775.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000471728.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000472139.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000487450.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	ENST00000626989.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	NM_000447.2	Refseq
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	NM_012486.2	Refseq
Affymetrix Human Clariom D Assay	PSR0100187111.hg.1	TC0100011811.hg.1	Clariom D TC