Hs01598445_m1

• Gene Symbol: PSEN2
• Gene Name: presenilin 2
• Gene Aliases: AD3L, AD4, CMD1V, PS2, STM2
• Chromosome Location: Chr.1: 226870572 - 226903829 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PSEN2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000447.2	NP_000438.2	11 - 12	1498		154
	XM_005273199.3	XP_005273256.1	10 - 11	1311		154
	XM_017001835.1	XP_016857324.1	10 - 11	1819		154
GenBank mRNA	AF416718.1	-	9 - 10	1139		154
	AK301143.1	-	10 - 11	1247		154
	BC006365.2	-	12 - 13	1692	4131408	154
	BT006984.1	-	9 - 10	1071		154
	L43964.1	-	10 - 11	1438		154
	L44577.1	-	11 - 12	1436		154

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC01001865.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Protease, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PSEN2

Panther Classification:

Molecular Function -

aspartic protease

Gene Ontology Categories:

Process(es)

response to hypoxia
membrane protein ectodomain proteolysis
calcium ion transport
Notch signaling pathway
Notch receptor processing
protein processing
membrane protein intracellular domain proteolysis
intracellular signal transduction
amyloid precursor protein catabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of catalytic activity
ephrin receptor signaling pathway
beta-amyloid metabolic process

Function(s)

endopeptidase activity
aspartic-type endopeptidase activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	TC01001865.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	ENST00000340188.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	ENST00000366782.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	ENST00000366783.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	ENST00000391872.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	ENST00000422240.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	ENST00000471728.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	ENST00000472139.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	NM_000447.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR01029022.hg.1	NM_012486.2	Refseq