Hs02561894_s1

• Gene Symbol: NCK2
• Gene Name: NCK adaptor protein 2
• Gene Aliases: GRB4, NCKbeta
• Chromosome Location: Chr.2: 105744649 - 105894274 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: NCK2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001004720.2	NP_001004720.1	3	857		71
	NM_003581.4	NP_003572.2	4	967		71
	XM_006712797.3	XP_006712860.1	4	1623		71
	XM_011511991.2	XP_011510293.1	4	1061		71
	XM_017005103.1	XP_016860592.1	5	1225		71
	XM_017005104.1	XP_016860593.1	4	1237		71
	XM_017005105.1	XP_016860594.1	4	974		71
GenBank mRNA	AF043119.1	-	2	719		71
	AF047487.1	-	3	823		71
	BC000103.2	-	3	741	3505427	71
	BC007195.1	-	3	748	3608149	71
	KU178418.1	-	2	691		71

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene NCK2

Gene Ontology Categories:

Process(es)

immunological synapse formation
actin filament organization
signal transduction
signal complex assembly
epidermal growth factor receptor signaling pathway
regulation of epidermal growth factor-activated receptor activity
negative regulation of cell population proliferation
vesicle-mediated transport
cell migration
lamellipodium assembly
positive regulation of actin filament polymerization
negative regulation of peptidyl-serine phosphorylation
positive regulation of translation in response to endoplasmic reticulum stress
positive regulation of T cell proliferation
T cell activation
positive regulation of GTPase activity
positive regulation of transcription by RNA polymerase II
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
dendritic spine development
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
negative regulation of PERK-mediated unfolded protein response
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

protein binding
cytoskeletal anchor activity
signaling receptor complex adaptor activity
protein-containing complex binding
scaffold protein binding