Hs03043899_m1

• Gene Symbol: MCL1
• Gene Name: BCL2 family apoptosis regulator
• Gene Aliases: BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
• Chromosome Location: Chr.1: 150574551 - 150579738 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MCL1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001197320.1	NP_001184249.1	3 - 4	682		99
	NM_021960.4	NP_068779.1	2 - 3	1141		99
GenBank mRNA	AF118124.1	-	2 - 3	982		99
	AK294462.1	-	3 - 4	713		99
	AK297217.1	-	3 - 4	677		99
	AK300499.1	-	3 - 4	787		99
	AK304775.1	-	3 - 4	823		99
	AK312508.1	-	2 - 3	1013		99
	AK316267.1	-	3 - 4	969		99
	BC017197.2	-	2 - 3	987	3138465	99
	BC071897.1	-	2 - 3	989	6586159	99
	BC107735.1	-	2 - 3	1004	4770487	99
	BT006640.1	-	2 - 3	933		99
	FJ917536.1	-	3 - 4	474		99
	L08246.1	-	2 - 3	993		99

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Apoptosis, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MCL1

Gene Ontology Categories:

Process(es)

cell fate determination
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cellular homeostasis
response to cytokine
negative regulation of apoptotic process
protein transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway

Function(s)

protein binding
protein channel activity
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding