Hs03653961_m1

• Gene Symbol: PFKL
• Gene Name: phosphofructokinase, liver type
• Gene Aliases: ATP-PFK, PFK-B, PFK-L
• Chromosome Location: Chr.21: 44300034 - 44327381 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PFKL
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001002021.2	NP_001002021.2	1 - 2	155		59
	XM_006724011.1	XP_006724074.1	1 - 2	101		59
	XM_017028369.1	XP_016883858.1	1 - 2	119		59
	XM_017028370.1	XP_016883859.1	1 - 2	100		59
GenBank mRNA	BC006422.1	-	1 - 2	101	4040291	59

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	CD615222.1	-	1 - 2	91		Chr. 21 - 44300100 - 44306719 [+] on Build GRCh38	59
GenBankmRNA	AL561322.3	-	1 - 2	122		Chr. 21 - 44300067 - 44314020 [+] on Build GRCh38	59
GenBankmRNA	CR983723.1	-	1 - 2	133		Chr. 21 - 44300056 - 44304455 [+] on Build GRCh38	59
GenBankmRNA	CD615219.1	-	4 - 5			Chr. 21 - 44300101 - 44306719 [-] on Build GRCh38	59
GenBankmRNA	CD615220.1	-	1 - 2	92		Chr. 21 - 44300100 - 44306719 [+] on Build GRCh38	59
GenBankmRNA	BG488542.1	-	1 - 2	102		Chr. 21 - 44300088 - 44305936 [+] on Build GRCh38	59
GenBankmRNA	CD615221.1	-	4 - 5			Chr. 21 - 44300100 - 44306719 [-] on Build GRCh38	59

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	autoimmune regulator	AIRE	AIRE1, APECED, APS1, APSI, PGA1	-1.8kb	Sense	Chr. 21 - 44285838 - 44298219 on NCBI Build GRCh38
Downstream	chromosome 21 open reading frame 2	C21orf2	LRRC76, YF5/A2	24.5kb	Anti-sense	Chr. 21 - 44328944 - 44339417 on NCBI Build GRCh38

More Information

Additional Information:

This assay is in the 5'UTR region of the BC006422.1, NM_001002021.2, XM_006724011.1, XM_017028369.1, XM_017028370.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PFKL

Panther Classification:

Molecular Function -

carbohydrate kinase, kinase, transferase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

fructose 6-phosphate metabolic process
glycolytic process
response to glucose
fructose 1,6-bisphosphate metabolic process
negative regulation of insulin secretion
protein oligomerization
protein homotetramerization
canonical glycolysis

Function(s)

6-phosphofructokinase activity
protein binding
ATP binding
kinase binding
identical protein binding
metal ion binding
fructose binding
fructose-6-phosphate binding