Hs03678487_m1

• Gene Symbol: TNFRSF10B
• Gene Name: TNF receptor superfamily member 10b
• Gene Aliases: CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
• Chromosome Location: Chr.8: 23020133 - 23069187 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TNFRSF10B
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_027140.1		1 - 2	439		102
GenBank mRNA	AK298602.1	-	1 - 2	283		102
	FJ200482.1	-	1 - 2	146		102

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	BE563253.1	-		251		Chr. - - [-] on Build	102
GenBankmRNA	CN314032.1	-	1 - 2	322		Chr. 8 - 23029607 - 23069068 [-] on Build GRCh38	102
GenBankmRNA	DC428518.1	-	1 - 2	285		Chr. 8 - 23028558 - 23069031 [-] on Build GRCh38	102
GenBankmRNA	BP313702.1	-	1 - 2	274		Chr. 8 - 23028518 - 23069022 [-] on Build GRCh38	102
GenBankmRNA	AA232440.1	-	1 - 2	253		Chr. 8 - 23030799 - 23069002 [-] on Build GRCh38	102
GenBankmRNA	CN314036.1	-	1 - 2	248		Chr. 8 - 23028550 - 23068993 [-] on Build GRCh38	102
GenBankmRNA	DA331621.1	-	1 - 2	283		Chr. 8 - 23028517 - 23069031 [-] on Build GRCh38	102
GenBankmRNA	DC425547.1	-	1 - 2	274		Chr. 8 - 23029607 - 23069022 [-] on Build GRCh38	102
GenBankmRNA	DC418302.1	-	1 - 2	274		Chr. 8 - 23028534 - 23069022 [-] on Build GRCh38	102
GenBankmRNA	DC415507.1	-	1 - 2	289		Chr. 8 - 23028559 - 23069036 [-] on Build GRCh38	102
GenBankmRNA	DC332980.1	-	1 - 2	283		Chr. 8 - 23028574 - 23069031 [-] on Build GRCh38	102
GenBankmRNA	DA460638.1	-	1 - 2	298		Chr. 8 - 23029639 - 23069046 [-] on Build GRCh38	102

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	tumor necrosis factor receptor superfamily member 10d, decoy with truncated death domain pseudogene	LOC286059			Anti-sense	Chr. 8 - 23068229 - 23083619 on NCBI Build GRCh38
Downstream	uncharacterized LOC254896	LOC254896		15.2kb	Anti-sense	Chr. 8 - 23084355 - 23103558 on NCBI Build GRCh38

More Information

Additional Information:

This assay is in the 5'UTR region of the AK298602.1 transcripts.

• Set Membership: Amplicon length greater than or equal to 101, Homo sapiens, Probe spans exons

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
immune response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
multicellular organism development
extrinsic apoptotic signaling pathway via death domain receptors
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to endoplasmic reticulum stress
regulation of cell proliferation
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to mechanical stimulus
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors

Function(s)

receptor activity
tumor necrosis factor-activated receptor activity
protein binding
TRAIL binding