Hs03835407_s1

• Gene Symbol: ZAP70
• Gene Name: zeta chain of T cell receptor associated protein kinase 70
• Gene Aliases: ADMIO2, IMD48, SRK, STCD, STD, TZK, ZAP-70
• Chromosome Location: Chr.2: 97712030 - 97744327 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ZAP70
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_017004867.1	XP_016860356.1	1			82
	XM_017004868.1	XP_016860357.1	1			82
	XM_017004869.1	XP_016860358.1	1			82
	XM_017004870.1	XP_016860359.1	1			82

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	BC133674.1	-	1	253		Chr. 2 - 97712795 - 97713373 [-] on Build GRCh38	82

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	long intergenic non-protein coding RNA 1125	LINC01125		-9.7kb	Anti-sense	Chr. 2 - 97669743 - 97703066 on NCBI Build GRCh38

More Information

Additional Information:

This assay is in the 5'UTR region of the XM_017004867.1, XM_017004868.1, XM_017004869.1, XM_017004870.1 transcripts.

• Set Membership: Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Gene Ontology Categories:

Process(es)

adaptive immune response
macrophage activation involved in immune response
neutrophil activation involved in immune response
protein phosphorylation
inflammatory response
immune response
transmembrane receptor protein tyrosine kinase signaling pathway
peptidyl-tyrosine phosphorylation
T cell differentiation
positive regulation of cell adhesion mediated by integrin
intracellular signal transduction
peptidyl-tyrosine autophosphorylation
T cell activation
B cell activation
positive regulation of mast cell degranulation
beta selection
positive thymic T cell selection
negative thymic T cell selection
innate immune response
positive regulation of B cell differentiation
positive regulation of T cell differentiation
positive regulation of alpha-beta T cell differentiation
positive regulation of alpha-beta T cell proliferation
positive regulation of calcium-mediated signaling
T cell receptor signaling pathway
B cell receptor signaling pathway
T cell aggregation
T cell migration
regulation of platelet aggregation

Function(s)

phosphotyrosine binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
receptor binding
protein binding
ATP binding