Hs03866877_s1

• Gene Symbol: NCK1
• Gene Name: NCK adaptor protein 1
• Gene Aliases: NCK, NCKalpha, nck-1
• Chromosome Location: Chr.3: 136862208 - 136951610 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: NCK1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001190796.2	NP_001177725.1	3	4102		68
	NM_001291999.1	NP_001278928.1	4	4372		68
	NM_006153.5	NP_006144.1	4	4338		68
GenBank mRNA	AK095534.1	-	1	2248		68

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	BU741687.1	-	1			Chr. 3 - 136950909 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	BM980075.1	-	1			Chr. 3 - 136950891 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	BU963605.1	-	1	331		Chr. 3 - 136951199 - 136951605 [+] on Build GRCh38	68
GenBankmRNA	AA772352.1	-	1			Chr. 3 - 136951129 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	AA904483.1	-	1			Chr. 3 - 136951285 - 136951601 [-] on Build GRCh38	68
GenBankmRNA	CB241256.1	-	1			Chr. 3 - 136950917 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	AW316972.1	-	1			Chr. 3 - 136951135 - 136951605 [-] on Build GRCh38	68
GenBankmRNA	AI657055.1	-	1			Chr. 3 - 136951123 - 136951606 [-] on Build GRCh38	68
GenBankmRNA	AI637920.1	-	1			Chr. 3 - 136951123 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	BU675126.1	-	1			Chr. 3 - 136950915 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	CB241276.1	-	1			Chr. 3 - 136950957 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	AI676064.1	-	1			Chr. 3 - 136951231 - 136951614 [-] on Build GRCh38	68
GenBankmRNA	BF477693.1	-	1			Chr. 3 - 136951231 - 136951614 [-] on Build GRCh38	68

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	NCK1 antisense RNA 1 (head to head)	NCK1-AS1	SLC35G2-AS1	-87.2kb	Anti-sense	Chr. 3 - 136841976 - 136862063 on NCBI Build GRCh38
Downstream	interleukin 20 receptor subunit beta	IL20RB	DIRS1, FNDC6, IL-20R2	6.3kb	Sense	Chr. 3 - 136957865 - 137011085 on NCBI Build GRCh38

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, 3' Most, Detect Genomic DNA, Homo sapiens, 1700, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene NCK1

Gene Ontology Categories:

Process(es)

negative regulation of protein kinase activity
substrate-dependent cell migration, cell extension
actin filament organization
signal complex assembly
vesicle-mediated transport
lamellipodium assembly
positive regulation of actin filament polymerization
negative regulation of peptidyl-serine phosphorylation
positive regulation of translation in response to endoplasmic reticulum stress
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of T cell proliferation
T cell activation
positive regulation of GTPase activity
positive regulation of transcription by RNA polymerase II
vascular endothelial growth factor receptor signaling pathway
T cell receptor signaling pathway
response to other organism
negative regulation of cell death
peptidyl-serine dephosphorylation
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of cap-dependent translational initiation
positive regulation of cap-independent translational initiation
negative regulation of PERK-mediated unfolded protein response
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress

Function(s)

protein kinase inhibitor activity
signaling receptor binding
protein binding
cytoskeletal anchor activity
protein domain specific binding
signaling receptor complex adaptor activity
protein-macromolecule adaptor activity
receptor tyrosine kinase binding
eukaryotic initiation factor eIF2 binding
cadherin binding involved in cell-cell adhesion

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	150241	-	-