Hs03899596_s1

• Gene Symbol: FAS
• Gene Name: Fas cell surface death receptor
• Gene Aliases: ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6
• Chromosome Location: Chr.10: 88968429 - 89017061 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: FAS
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000043.5	NP_000034.1	9	3254		78
	NM_001320619.1	NP_001307548.1	8	3171		78
	NM_152871.3	NP_690610.1	8	3191		78
	NM_152872.3	NP_690611.1	8	3229		78
	NR_028033.3		7	3082		78
	NR_028034.3		6	2944		78
	NR_028035.3		7	3007		78
	NR_028036.3		8	3145		78
	NR_135313.1		7	3062		78
	NR_135314.1		9	3245		78
	NR_135315.1		7	2998		78
GenBank mRNA	AK026195.1	-	1	543		78

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	BX093666.1	-	1	309		Chr. 10 - 89016070 - 89016855 [+] on Build GRCh38	78

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	FAS antisense RNA 1	FAS-AS1	FAS-AS, FASAS, SAF	-22.9kb	Anti-sense	Chr. 10 - 88991422 - 88992975 on NCBI Build GRCh38
Downstream	microRNA 4679-2	MIR4679-2		46.3kb	Anti-sense	Chr. 10 - 89063335 - 89063411 on NCBI Build GRCh38

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, 3' Most, Detect Genomic DNA, Homo sapiens, 1700, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene FAS

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

ovarian follicle atresia
immunoglobulin production
renal system process
protein complex assembly
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
activation-induced cell death of T cells
inflammatory cell apoptotic process
inflammatory response
immune response
signal transduction
spermatogenesis
brain development
aging
circadian rhythm
extrinsic apoptotic signaling pathway via death domain receptors
response to toxic substance
gene expression
regulation of gene expression
B cell mediated immunity
telencephalon development
dendrite regeneration
positive regulation of protein homooligomerization
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
regulation of cell proliferation
response to drug
ovulation cycle
regulation of apoptotic process
chordate embryonic development
positive regulation of apoptotic process
negative regulation of apoptotic process
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAPK cascade
response to peptide hormone
negative thymic T cell selection
regulation of lymphocyte differentiation
regulation of myeloid cell differentiation
response to cycloheximide
spleen development
negative regulation of B cell activation
protein homooligomerization
response to glucocorticoid
maternal process involved in female pregnancy
positive regulation of lymphocyte apoptotic process
cellular response to hydrogen peroxide
response to growth factor
cellular response to phenylalanine
cellular response to mechanical stimulus
cellular response to cobalt ion
cellular response to lithium ion
cellular response to glucose stimulus
cellular response to interleukin-1
cellular response to estrogen stimulus
cellular response to hyperoxia
cellular response to hypoxia
cellular response to hydrostatic pressure
motor neuron apoptotic process
apoptotic signaling pathway
extrinsic apoptotic signaling pathway
extrinsic apoptotic signaling pathway in absence of ligand
hepatocyte apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
liver regeneration
necroptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
response to fluoride
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protease binding
signal transducer activity
receptor activity
tumor necrosis factor-activated receptor activity
protein binding
kinase binding
protein complex binding
identical protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC1000008390.hg.1	ENST00000562983.1	Ensembl
Affymetrix Human Clariom D Assay	TC1000008390.hg.1	ENST00000562983.1	Ensembl

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	102335	-	-