Hs03905157_s1

• Gene Symbol: KCNB1
• Gene Name: potassium voltage-gated channel subfamily B member 1
• Gene Aliases: DRK1, Kv2.1
• Chromosome Location: Chr.20: 49363877 - 49484033 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: KCNB1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_004975.3	NP_004966.1	2	11618		76
	XM_006723784.3	XP_006723847.1	3	11712		76
	XM_011528799.2	XP_011527101.1	3	11741		76
GenBank mRNA	AK126976.1	-	1	3651		76

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	BM703844.1	-	1	278		Chr. 20 - 49363912 - 49364370 [-] on Build GRCh38	76
GenBankmRNA	BU728497.1	-	1			Chr. 20 - 49363877 - 49364414 [+] on Build GRCh38	76
GenBankmRNA	BU736654.1	-	1			Chr. 20 - 49363877 - 49364406 [+] on Build GRCh38	76
GenBankmRNA	BM685769.1	-		180		Chr. - - [-] on Build	76
GenBankmRNA	DB305167.1	-	1			Chr. 20 - 49363886 - 49364430 [+] on Build GRCh38	76
GenBankmRNA	DB304144.1	-	1			Chr. 20 - 49363879 - 49364374 [+] on Build GRCh38	76
GenBankmRNA	BM704484.1	-	1	298		Chr. 20 - 49363880 - 49364403 [-] on Build GRCh38	76
GenBankmRNA	AI057291.1	-	1			Chr. 20 - 49363880 - 49364278 [+] on Build GRCh38	76
GenBankmRNA	BX119683.1	-	1	271		Chr. 20 - 49363877 - 49364376 [-] on Build GRCh38	76
GenBankmRNA	BM668821.1	-	1			Chr. 20 - 49363877 - 49364370 [+] on Build GRCh38	76

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	ZNFX1 antisense RNA 1	ZFAS1	C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1	-74.6kb	Anti-sense	Chr. 20 - 49278178 - 49289260 on NCBI Build GRCh38
Downstream	prostaglandin I2 (prostacyclin) synthase	PTGIS	CYP8, CYP8A1, PGIS, PTGI	136.1kb	Sense	Chr. 20 - 49503874 - 49568170 on NCBI Build GRCh38

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Ion Channel, 3' Most, Detect Genomic DNA, Homo sapiens, 1700, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene KCNB1

Panther Classification:

Molecular Function -

voltage-gated ion channel

Gene Ontology Categories:

Process(es)

action potential
vesicle docking involved in exocytosis
glutamate receptor signaling pathway
positive regulation of norepinephrine secretion
cellular response to nutrient levels
positive regulation of catecholamine secretion
regulation of ion transmembrane transport
glucose homeostasis
positive regulation of calcium ion-dependent exocytosis
negative regulation of insulin secretion
regulation of insulin secretion
protein homooligomerization
cellular response to glucose stimulus
potassium ion transmembrane transport
protein targeting to plasma membrane
positive regulation of protein targeting to membrane
regulation of action potential
positive regulation of long term synaptic depression
regulation of motor neuron apoptotic process

Function(s)

delayed rectifier potassium channel activity
protein binding
ubiquitin-like protein binding
ion channel binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	142318	-	-
ABI Human Genome Survey Microarray Version 2.0	157406	-	-