Hs04183413_m1

• Gene Symbol: PITX2
• Gene Name: paired like homeodomain 2
• Gene Aliases: ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS
• Chromosome Location: Chr.4: 110617423 - 110642123 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PITX2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000325.5	NP_000316.2	1 - 2	840		97
GenBank mRNA	AF048722.1	-	1 - 2	795		97
	AK313987.1	-	1 - 2	495		97
	BC013998.2	-	1 - 2	839	3937807	97

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0400011600.hg.1
This assay targets the same location as HTA transcript cluster(s) TC04001471.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PITX2

Panther Classification:

Molecular Function -

homeodomain transcription factor

Gene Ontology Categories:

Process(es)

patterning of blood vessels
vasculogenesis
in utero embryonic development
neuron migration
extraocular skeletal muscle development
atrioventricular valve development
cardiac neural crest cell migration involved in outflow tract morphogenesis
pulmonary myocardium development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
determination of left/right symmetry
myoblast fusion
male gonad development
female gonad development
response to hormone
Wnt signaling pathway
subthalamic nucleus development
hypothalamus cell migration
regulation of cell migration
embryonic camera-type eye development
response to vitamin A
embryonic hindlimb morphogenesis
hair cell differentiation
vascular smooth muscle cell differentiation
deltoid tuberosity development
odontogenesis of dentin-containing tooth
odontogenesis
camera-type eye development
positive regulation of DNA binding
positive regulation of transcription from RNA polymerase II promoter
spleen development
embryonic digestive tract morphogenesis
atrial cardiac muscle tissue morphogenesis
ventricular cardiac muscle cell development
somatotropin secreting cell differentiation
prolactin secreting cell differentiation
ventricular septum morphogenesis
left lung morphogenesis
pulmonary vein morphogenesis
superior vena cava morphogenesis
endodermal digestive tract morphogenesis
iris morphogenesis
cell proliferation involved in outflow tract morphogenesis
left/right axis specification
positive regulation of myoblast proliferation

Function(s)

transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II activating transcription factor binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
protein binding
transcription factor binding
chromatin DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	TC04001471.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	ENST00000306732.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	ENST00000354925.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	ENST00000355080.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	ENST00000394598.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	NM_000325.5	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	NM_001204397.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	NM_001204398.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	NM_001204399.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	NM_153426.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR04020910.hg.1	NM_153427.2	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000306732.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000354925.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000355080.9	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000394598.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000511837.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000511990.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000557119.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000613094.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000614423.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000616641.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_000325.5	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_001204397.1	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_001204398.1	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_001204399.1	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_153426.2	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_153427.2	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000306732.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000354925.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000355080.9	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000394598.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000511837.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000511990.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000557119.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000613094.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000614423.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	ENST00000616641.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_000325.5	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_001204397.1	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_001204398.1	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_001204399.1	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_153426.2	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	NM_153427.2	Refseq
Affymetrix Human Clariom D Assay	PSR0400179694.hg.1	TC0400011600.hg.1	Clariom D TC