Hs04183449_g1

• Gene Symbol: SMPD1
• Gene Name: sphingomyelin phosphodiesterase 1
• Gene Aliases: ASM, ASMASE, NPD
• Chromosome Location: Chr.11: 6390301 - 6394998 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SMPD1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000543.4	NP_000534.3	3 - 4	1441		104
	NM_001007593.2	NP_001007594.2	3 - 4	1438		104
	NM_001318087.1	NP_001305016.1	3 - 4	1441		104
	NM_001318088.1	NP_001305017.1	3 - 4	1481		104
	NR_134502.1		3 - 4	788		104
GenBank mRNA	AB209775.1	-	3 - 4	1424		104
	AK292388.1	-	3 - 4	1372		104
	AY649987.1	-	3 - 4	620		104
	HQ132745.1	-	3 - 4	1250		104
	HQ132746.1	-	3 - 4	1181		104
	HQ132747.1	-	3 - 4	1250		104
	M59916.1	-	3 - 4	1350		104
	X52678.1	-	2 - 3	869		104
	X59960.1	-	3 - 4	1366		104

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC11000131.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SMPD1

Panther Classification:

Molecular Function -

hydrolase, phosphodiesterase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sphingomyelin metabolic process
sphingomyelin catabolic process
glycosphingolipid metabolic process
signal transduction
nervous system development
termination of signal transduction
positive regulation of protein dephosphorylation
response to cocaine
response to drug
positive regulation of apoptotic process
negative regulation of MAP kinase activity
ceramide biosynthetic process

Function(s)

sphingomyelin phosphodiesterase activity
protein binding
zinc ion binding
hydrolase activity, acting on glycosyl bonds
acid sphingomyelin phosphodiesterase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR11001871.hg.1	ENST00000299397.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11001871.hg.1	ENST00000342245.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11001871.hg.1	ENST00000356761.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11001871.hg.1	ENST00000527275.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11001871.hg.1	NM_000543.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11001871.hg.1	NM_001007593.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11001871.hg.1	TC11000131.hg.1	HTA TC