Hs04234836_s1 Best Coverage

• Gene Symbol: SOX2
• Gene Name: SRY-box 2
• Gene Aliases: ANOP3, MCOPS3
• Chromosome Location: Chr.3: 181711924 - 181714436 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SOX2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003106.3	NP_003097.1	1	1153		86
GenBank mRNA	AK312595.1	-	2	1082		86
	BC013923.2	-	1	791	2823424	86
	L07335.1	-	1	746		86
	Z31560.1	-	1	728		86

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Recommended Assay, Homo sapiens, Inventoried, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SOX2

Panther Classification:

Molecular Function -

HMG box transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
osteoblast differentiation
eye development
endodermal cell fate specification
chromatin organization
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell cycle arrest
response to wounding
regulation of gene expression
glial cell fate commitment
pituitary gland development
adenohypophysis development
positive regulation of cell-cell adhesion
forebrain development
somatic stem cell population maintenance
tissue regeneration
regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAPK cascade
positive regulation of cell differentiation
negative regulation of neuron differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
inner ear development
negative regulation of epithelial cell proliferation
response to growth factor
negative regulation of canonical Wnt signaling pathway
neuronal stem cell population maintenance

Function(s)

transcription regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
miRNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0800008767.hg.1	ENST00000517740.1	Ensembl
Affymetrix Human Clariom D Assay	TC0800008767.hg.1	ENST00000517740.1	Ensembl