Hs04264245_m1

• Gene Symbol: PTPRC
• Gene Name: protein tyrosine phosphatase, receptor type C
• Gene Aliases: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
• Chromosome Location: Chr.1: 198638968 - 198757476 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PTPRC
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_080921.3	NP_563578.2	3 - 4	312		61
GenBank mRNA	AK292131.1	-	3 - 4	185		61
	DA670254.1	-	3 - 4	215		61
	DA819314.1	-	3 - 4	312		61
	Y00062.1	-	4 - 5	239		61

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC01001640.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PTPRC

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of T cell mediated cytotoxicity
negative regulation of cytokine-mediated signaling pathway
hematopoietic progenitor cell differentiation
immunoglobulin biosynthetic process
negative regulation of protein kinase activity
protein dephosphorylation
negative regulation of cell adhesion involved in substrate-bound cell migration
cell surface receptor signaling pathway
dephosphorylation
T cell differentiation
positive regulation of B cell proliferation
peptidyl-tyrosine dephosphorylation
B cell proliferation
positive regulation of T cell proliferation
cell cycle phase transition
positive regulation of protein kinase activity
bone marrow development
stem cell development
T cell receptor signaling pathway
B cell receptor signaling pathway
positive regulation of antigen receptor-mediated signaling pathway
release of sequestered calcium ion into cytosol
defense response to virus
regulation of cell cycle
positive regulation of hematopoietic stem cell migration
positive regulation of stem cell proliferation

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
protein kinase binding