Hs04398988_m1

• Gene Symbol: TGFB3
• Gene Name: transforming growth factor beta 3
• Gene Aliases: ARVD, ARVD1, LDS5, RNHF, TGF-beta3
• Chromosome Location: Chr.14: 75958097 - 75982022 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TGFB3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003239.3	NP_003230.1	1 - 2	1482		103
GenBank mRNA	AK313564.1	-	1 - 2	563		103
	BC018503.1	-	1 - 2	453	4477175	103
	BT007287.1	-	1 - 2	353		103
	EF560714.1	-	1 - 2	466		103
	J03241.1	-	1 - 2	615		103
	X14149.1	-	1 - 2	606		103

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC14001326.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TGFB3

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
response to hypoxia
in utero embryonic development
platelet degranulation
transforming growth factor beta receptor signaling pathway
SMAD protein import into nucleus
salivary gland morphogenesis
female pregnancy
aging
negative regulation of DNA replication
negative regulation of cell proliferation
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
negative regulation of macrophage cytokine production
cell growth
positive regulation of bone mineralization
negative regulation of transforming growth factor beta receptor signaling pathway
mammary gland development
response to progesterone
positive regulation of collagen biosynthetic process
response to laminar fluid shear stress
wound healing
regulation of cell proliferation
odontogenesis
uterine wall breakdown
regulation of apoptotic process
positive regulation of apoptotic process
regulation of MAPK cascade
negative regulation of neuron apoptotic process
response to estrogen
ossification involved in bone remodeling
cell-cell junction organization
positive regulation of DNA replication
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
lung alveolus development
digestive tract development
embryonic neurocranium morphogenesis
inner ear development
positive regulation of protein secretion
positive regulation of filopodium assembly
positive regulation of stress fiber assembly
positive regulation of cell division
palate development
face morphogenesis
frontal suture morphogenesis
positive regulation of SMAD protein import into nucleus
SMAD protein signal transduction
detection of hypoxia
regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
positive regulation of occluding junction disassembly

Function(s)

type II transforming growth factor beta receptor binding
cytokine activity
protein binding
growth factor activity
type I transforming growth factor beta receptor binding
type III transforming growth factor beta receptor binding
identical protein binding
protein heterodimerization activity
transforming growth factor beta binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR14015141.hg.1	ENST00000238682.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR14015141.hg.1	ENST00000556285.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR14015141.hg.1	NM_003239.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR14015141.hg.1	TC14001326.hg.1	HTA TC