Hs04401723_m1

• Gene Symbol: NEDD4
• Gene Name: neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
• Gene Aliases: NEDD4-1, RPF1
• Chromosome Location: Chr.15: 55826917 - 55993746 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: NEDD4
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_104302.1		17 - 18	3644		111
GenBank mRNA	AL833293.1	-	18 - 19	2982		111

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	protogenin	PRTG	IGDCC5	-90.4kb	Sense	Chr. 15 - 55611540 - 55743649 on NCBI Build GRCh38
Downstream	regulatory factor X7	RFX7	RFXDC2	252.4kb	Sense	Chr. 15 - 56090533 - 56247654 on NCBI Build GRCh38

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1500009508.hg.1

• Set Membership: Amplicon length greater than or equal to 101, Homo sapiens, Probe spans exons

Gene Ontology Categories:

Process(es)

adaptive immune response
outflow tract morphogenesis
endocardial cushion development
protein monoubiquitination
protein targeting to lysosome
lysosomal transport
neuromuscular junction development
negative regulation of sodium ion transport
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
positive regulation of phosphatidylinositol 3-kinase signaling
response to denervation involved in regulation of muscle adaptation
regulation of macroautophagy
protein ubiquitination
transmission of virus
negative regulation of vascular endothelial growth factor receptor signaling pathway
neuron projection development
receptor internalization
receptor catabolic process
cellular response to UV
regulation of ion transmembrane transport
T cell activation
regulation of membrane potential
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
glucocorticoid receptor signaling pathway
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
development involved in symbiotic interaction
positive regulation of protein catabolic process
positive regulation of nucleocytoplasmic transport
blood vessel morphogenesis
regulation of dendrite morphogenesis
regulation of synapse organization
progesterone receptor signaling pathway
response to calcium ion
protein K63-linked ubiquitination
regulation of potassium ion transmembrane transporter activity
negative regulation of sodium ion transmembrane transporter activity

Function(s)

protein binding
protein C-terminus binding
ligase activity
sodium channel inhibitor activity
protein domain specific binding
beta-2 adrenergic receptor binding
ubiquitin binding
phosphoserine binding
phosphothreonine binding
ubiquitin protein ligase activity
RNA polymerase binding
proline-rich region binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000338963.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000435532.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000503468.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000506154.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000508342.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000508871.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_001284338.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_001284339.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_001284340.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_006154.3	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_198400.3	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NR_104302.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000338963.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000435532.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000503468.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000506154.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000508342.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	ENST00000508871.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_001284338.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_001284339.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_001284340.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_006154.3	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NM_198400.3	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	NR_104302.1	Refseq
Affymetrix Human Clariom D Assay	PSR1500170177.hg.1	TC1500009508.hg.1	Clariom D TC