Hs04403386_m1

• Gene Symbol: CSF1R
• Gene Name: colony stimulating factor 1 receptor
• Gene Aliases: C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
• Chromosome Location: Chr.5: 150053291 - 150113372 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: CSF1R
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_109969.1		13 - 14	2183		81
GenBank mRNA	AB208819.1	-	13 - 14	2133		81

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	HMG-box containing 3	HMGXB3	HMGX3, SMF	-4.4kb	Anti-sense	Chr. 5 - 150000606 - 150053143 on NCBI Build GRCh38
Downstream	platelet derived growth factor receptor beta	PDGFRB	CD140B, IBGC4, IMF1, JTK12, KOGS, PDGFR, PDGFR-1, PDGFR1, PENTT	52.9kb	Sense	Chr. 5 - 150113839 - 150155884 on NCBI Build GRCh38

More Information

• Set Membership: Amplicon length between 71 and 85, Homo sapiens, Probe spans exons

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of protein phosphorylation
inflammatory response
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
multicellular organism development
axon guidance
skeletal muscle tissue development
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
regulation of cell shape
peptidyl-tyrosine phosphorylation
cytokine-mediated signaling pathway
olfactory bulb development
forebrain neuron differentiation
hemopoiesis
monocyte differentiation
macrophage differentiation
osteoclast differentiation
positive regulation of cell migration
ruffle organization
cellular response to macrophage colony-stimulating factor stimulus
macrophage colony-stimulating factor signaling pathway
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of apoptotic process
innate immune response
regulation of bone resorption
cell-cell junction maintenance
positive regulation of osteoclast differentiation
phosphatidylinositol metabolic process
protein autophosphorylation
phosphatidylinositol-mediated signaling
mammary gland duct morphogenesis
positive regulation of protein tyrosine kinase activity
positive regulation of ERK1 and ERK2 cascade
cellular response to cytokine stimulus
positive regulation of protein serine/threonine kinase activity
positive regulation of chemokine secretion
positive regulation of cell motility
regulation of actin cytoskeleton reorganization

Function(s)

macrophage colony-stimulating factor receptor activity
ATP binding
protein phosphatase binding
cytokine binding
protein homodimerization activity