Hs04406193_m1

• Gene Symbol: IL6ST
• Gene Name: interleukin 6 signal transducer
• Gene Aliases: CD130, CDW130, GP130, IL-6RB
• Chromosome Location: Chr.5: 55935095 - 55994993 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: IL6ST
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_120480.1		9 - 10	1331		89
	XM_017009441.1	XP_016864930.1	8 - 9	1187		89

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	interleukin 31 receptor A	IL31RA	CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, PLCA2, PRO21384, hGLM-R	-34.4kb	Anti-sense	Chr. 5 - 55840334 - 55922854 on NCBI Build GRCh38
Downstream	uncharacterized LOC441072	FLJ31104		35.5kb	Anti-sense	Chr. 5 - 55995167 - 56003649 on NCBI Build GRCh38

More Information

• Set Membership: Amplicon length between 86 and 100, Homo sapiens, Probe spans exons

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of acute inflammatory response
positive regulation of adaptive immune response
glycogen metabolic process
positive regulation of cell proliferation
regulation of Notch signaling pathway
positive regulation of vascular endothelial growth factor production
positive regulation of cardiac muscle hypertrophy
viral process
cytokine-mediated signaling pathway
response to cytokine
interleukin-11-mediated signaling pathway
oncostatin-M-mediated signaling pathway
positive regulation of T cell proliferation
positive regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of apoptotic process
positive regulation of osteoblast differentiation
positive regulation of astrocyte differentiation
leukemia inhibitory factor signaling pathway
interleukin-6-mediated signaling pathway
interleukin-27-mediated signaling pathway
ciliary neurotrophic factor-mediated signaling pathway

Function(s)

ciliary neurotrophic factor receptor activity
interleukin-6 receptor activity
interleukin-11 receptor activity
leukemia inhibitory factor receptor activity
oncostatin-M receptor activity
ciliary neurotrophic factor receptor binding
interleukin-6 receptor binding
protein binding
growth factor binding
interleukin-11 binding
interleukin-6 binding
protein homodimerization activity
interleukin-27 receptor activity