Hs04940094_m1

• Gene Symbol: RUNX2
• Gene Name: runt related transcription factor 2
• Gene Aliases: AML3, CBF-alpha-1, CBFA1, CCD, CCD1, CLCD, OSF-2, OSF2, PEA2aA, PEBP2aA
• Chromosome Location: Chr.6: 45328142 - 45664032 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: RUNX2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NR_103532.1		2 - 3	300		73
	NR_103533.1		2 - 3	265		73
GenBank mRNA	AW469546.1	-	1 - 2			73
	BX108677.1	-	2 - 3	253		73

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	AW296595.1	-	1 - 2			Chr. 6 - 45328412 - 45372055 [-] on Build GRCh38	73
GenBankmRNA	AW592551.1	-	1 - 2			Chr. 6 - 45328415 - 45372055 [-] on Build GRCh38	73
GenBankmRNA	AI738968.1	-	1 - 2			Chr. 6 - 45328396 - 45372045 [-] on Build GRCh38	73
GenBankmRNA	AA970073.1	-	1 - 2			Chr. 6 - 45328413 - 45372055 [-] on Build GRCh38	73
GenBankmRNA	AI394663.1	-	1 - 2			Chr. 6 - 45328661 - 45372048 [-] on Build GRCh38	73

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	microRNA 586	MIR586	MIRN586, hsa-mir-586	-130.9kb	Anti-sense	Chr. 6 - 45197674 - 45197770 on NCBI Build GRCh38
Downstream	uncharacterized LOC105375077	LOC105375077		182.3kb	Anti-sense	Chr. 6 - 45554330 - 45576791 on NCBI Build GRCh38

More Information

• Set Membership: Amplicon length between 71 and 85, 3' Most, Homo sapiens, Probe spans exons

Gene Ontology Categories:

Process(es)

ossification
osteoblast differentiation
endochondral ossification
osteoblast fate commitment
chondrocyte differentiation
chondrocyte development
osteoblast development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
hemopoiesis
neuron differentiation
T cell differentiation
BMP signaling pathway
positive regulation of chondrocyte differentiation
embryonic forelimb morphogenesis
regulation of fibroblast growth factor receptor signaling pathway
odontogenesis of dentin-containing tooth
regulation of odontogenesis of dentin-containing tooth
cellular response to fibroblast growth factor stimulus
regulation of cell differentiation
positive regulation of osteoblast differentiation
negative regulation of smoothened signaling pathway
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
cell maturation
embryonic cranial skeleton morphogenesis
stem cell differentiation
cellular response to BMP stimulus
positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Function(s)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
ATP binding
protein domain specific binding
histone deacetylase binding
bHLH transcription factor binding
repressing transcription factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000359524.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371432.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371436.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000371438.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000465038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000473041.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000473041.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000478660.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483243.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483243.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483243.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483243.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483243.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483243.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000483377.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000576263.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000625924.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000625924.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000625924.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000625924.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000625924.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000625924.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	ENST00000625924.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001015051.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001024630.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NM_001278478.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103532.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103532.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103532.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103532.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103532.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103532.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103533.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103533.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103533.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103533.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0600008146.hg.1	NR_103533.1	Refseq