Hs04971684_s1

• Gene Symbol: TIRAP
• Gene Name: TIR domain containing adaptor protein
• Gene Aliases: BACTS1, Mal, MyD88-2, wyatt
• Chromosome Location: Chr.11: 126281268 - 126294933 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TIRAP
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_017017161.1	XP_016872650.1	1	424		73

More Information

Additional Information:

This assay is in the 5'UTR region of the XM_017017161.1 transcripts.

• Set Membership: Amplicon length between 71 and 85, 3' Most, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Gene Ontology Categories:

Process(es)

MyD88-dependent toll-like receptor signaling pathway
inflammatory response
cell surface receptor signaling pathway
activation of NF-kappaB-inducing kinase activity
myeloid cell differentiation
positive regulation of B cell proliferation
response to lipopolysaccharide
regulation of interferon-beta production
positive regulation of interleukin-12 production
positive regulation of interleukin-15 production
positive regulation of interleukin-8 production
positive regulation of tumor necrosis factor production
positive regulation of toll-like receptor 2 signaling pathway
positive regulation of toll-like receptor 3 signaling pathway
toll-like receptor 4 signaling pathway
positive regulation of toll-like receptor 4 signaling pathway
TIRAP-dependent toll-like receptor 4 signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of growth of symbiont in host
innate immune response
regulation of innate immune response
positive regulation of interleukin-6 biosynthetic process
positive regulation of JNK cascade
defense response to Gram-positive bacterium
positive regulation of NF-kappaB transcription factor activity
positive regulation of ERK1 and ERK2 cascade
3'-UTR-mediated mRNA stabilization
cellular response to bacterial lipopeptide
cellular response to lipoteichoic acid
positive regulation of neutrophil chemotaxis
positive regulation of protein homodimerization activity
positive regulation of chemokine (C-X-C motif) ligand 1 production
positive regulation of chemokine (C-X-C motif) ligand 2 production

Function(s)

protein kinase C binding
protein binding
phosphatidylinositol-4,5-bisphosphate binding
protein binding, bridging
Toll-like receptor 4 binding
Toll-like receptor 2 binding
protein homodimerization activity
protein heterodimerization activity