Hs05024379_s1

• Gene Symbol: ITCH
• Gene Name: itchy E3 ubiquitin protein ligase
• Gene Aliases: ADMFD, AIF4, AIP4, NAPP1
• Chromosome Location: Chr.20: 34363235 - 34511773 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ITCH
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001257137.2	NP_001244066.1	26	4816		111
	NM_001257138.2	NP_001244067.1	24	4551		111
	NM_001324197.1	NP_001311126.1	26	4837		111
	NM_001324198.1	NP_001311127.1	25	4714		111
	NM_031483.6	NP_113671.3	25	4693		111
	XM_005260570.1	XP_005260627.1	24	4609		111
	XM_011529079.1	XP_011527381.1	24	4629		111
	XM_017028089.1	XP_016883578.1	25	4649		111
	XM_017028090.1	XP_016883579.1	26	4769		111
	XM_017028091.1	XP_016883580.1	24	4564		111

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	AJ308022.1	-	1			Chr. 20 - 34509543 - 34510010 [-] on Build GRCh38	111

More Information

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, 3' Most, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ITCH

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

regulation of cell growth
positive regulation of T cell anergy
ubiquitin-dependent protein catabolic process
apoptotic process
inflammatory response
Notch signaling pathway
protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
negative regulation of type I interferon production
protein K29-linked ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
innate immune response
positive regulation of protein catabolic process
negative regulation of JNK cascade
negative regulation of alpha-beta T cell proliferation
viral entry into host cell
negative regulation of defense response to virus
defense response to virus
nucleotide-binding oligomerization domain containing signaling pathway
protein K63-linked ubiquitination
protein K48-linked ubiquitination
regulation of protein deubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ligase activity
ubiquitin-like protein transferase activity
ribonucleoprotein complex binding
CXCR chemokine receptor binding
ubiquitin protein ligase activity