Hs05055090_s1

• Gene Symbol: DNA2
• Gene Name: DNA replication helicase/nuclease 2
• Gene Aliases: DNA2L, hDNA2
• Chromosome Location: Chr.10: 68414064 - 68472521 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DNA2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001080449.2	NP_001073918.2	16	2557		81
	NR_102264.1		17	2422		81
	XM_006717680.3	XP_006717743.1	17	2937		81
	XM_011539417.1	XP_011537719.1	10	1481		81
	XM_017015799.1	XP_016871288.1	13	1946		81
GenBank mRNA	AK307939.1	-	5	508		81
	AK308358.1	-	14	2199		81
	BC028188.1	-	3	423		81
	BC041115.2	-	4	575		81
	BC053574.1	-	6	751		81
	BC073945.1	-	2	164		81
	BC111740.1	-	17	2422	40038149	81
	D42046.1	-	16	2499		81

More Information

• Set Membership: Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Gene Ontology Categories:

Process(es)

DNA replication checkpoint
telomere maintenance via recombination
telomere maintenance
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA replication
mitochondrial DNA replication
base-excision repair
DNA duplex unwinding
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
mitotic telomere maintenance via semi-conservative replication

Function(s)

DNA binding
DNA helicase activity
helicase activity
nuclease activity
protein binding
ATP binding
ATPase activity
site-specific endodeoxyribonuclease activity, specific for altered base
5'-flap endonuclease activity
5'-3' DNA helicase activity
single-stranded DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding