Hs05312409_g1

• Gene Symbol: PDPK1
• Gene Name: 3-phosphoinositide dependent protein kinase 1
• Gene Aliases: PDK1, PDPK2, PDPK2P, PRO0461
• Chromosome Location: Chr.16: 2537964 - 2603190 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PDPK1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_011522521.2	XP_011520823.1	1	3553		102
	XM_011522523.2	XP_011520825.1	1	3558		102
	XM_017023271.1	XP_016878760.1	1	3558		102
	XM_017023275.1	XP_016878764.1	1	3564		102

More Information

Additional Information:

This assay is in the 5'UTR region of the XM_011522521.2, XM_011522523.2, XM_017023271.1, XM_017023275.1 transcripts.

• Set Membership: Amplicon length greater than or equal to 101, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

stimulatory C-type lectin receptor signaling pathway
type B pancreatic cell development
transcription, DNA-templated
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of protein kinase activity
hyperosmotic response
epidermal growth factor receptor signaling pathway
positive regulation of phospholipase activity
regulation of endothelial cell migration
negative regulation of cardiac muscle cell apoptotic process
cell migration
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
calcium-mediated signaling
actin cytoskeleton organization
platelet activation
negative regulation of transforming growth factor beta receptor signaling pathway
T cell costimulation
activation of protein kinase B activity
cellular response to insulin stimulus
negative regulation of toll-like receptor signaling pathway
intracellular signal transduction
Fc-epsilon receptor signaling pathway
regulation of I-kappaB kinase/NF-kappaB signaling
regulation of mast cell degranulation
protein autophosphorylation
phosphatidylinositol-mediated signaling
focal adhesion assembly
T cell receptor signaling pathway
positive regulation of release of sequestered calcium ion into cytosol
cellular response to epidermal growth factor stimulus
positive regulation of establishment of protein localization to plasma membrane
extrinsic apoptotic signaling pathway

Function(s)

protein serine/threonine kinase activity
3-phosphoinositide-dependent protein kinase activity
insulin receptor binding
protein binding
ATP binding
phospholipase activator activity
kinase activity
protein kinase binding
phospholipase binding