Hs06599540_s1

• Gene Symbol: TDG
• Gene Name: thymine DNA glycosylase
• Gene Aliases: hTDG
• Chromosome Location: Chr.12: 103965815 - 103988878 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TDG
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003211.4	NP_003202.3	2	376		100
	XM_005269125.1	XP_005269182.1	2	236		100
GenBank mRNA	AK299832.1	-	2	288		100
	AK309792.1	-	3	420		100
	AK313234.1	-	2	319		100
	AL710869.1	-	3	528		100
	BC019925.1	-	2	330		100
	BC037557.1	-	2	329	5184772	100
	BC104477.1	-	2	292		100
	DB162106.1	-	2	377		100

More Information

Additional Information:

This assay is in the 5'UTR region of the XM_005269125.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Homo sapiens, Amplicon spans exons and probe does not span exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TDG

Panther Classification:

Molecular Function -

DNA metabolism protein, DNA glycosylase, nucleic acid metabolism protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
base-excision repair
base-excision repair, AP site formation
mismatch repair
transcription, DNA-templated
embryo development
covalent chromatin modification
protein sumoylation
negative regulation of protein binding
oxidative DNA demethylation
negative regulation of chromatin binding
regulation of gene expression, epigenetic
depyrimidination
DNA demethylation

Function(s)

RNA polymerase II transcription cofactor activity
damaged DNA binding
double-stranded DNA binding
uracil DNA N-glycosylase activity
protein kinase C binding
protein binding
pyrimidine-specific mismatch base pair DNA N-glycosylase activity
DNA N-glycosylase activity
mismatched DNA binding
SUMO binding
protein homodimerization activity
structure-specific DNA binding