Hs06630396_s1

• Gene Symbol: MSH2
• Gene Name: mutS homolog 2
• Gene Aliases: COCA1, FCC1, HNPCC, HNPCC1, LCFS2
• Chromosome Location: Chr.2: 47403067 - 47634501 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MSH2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000251.2	NP_000242.1	7	1309		77
	NM_001258281.1	NP_001245210.1	8	1125		77
	XM_005264332.3	XP_005264389.2	7	1256		77
	XM_011532867.1	XP_011531169.1	7	1256		77
GenBank mRNA	AK222860.1	-	7	1246		77
	AK223284.1	-	7	1219		77
	AK296831.1	-	6	784		77
	AK297763.1	-	7	1012		77
	AK299667.1	-	6	644		77
	AK304496.1	-	8	1125		77
	AK311330.1	-	6	811		77
	BC021566.1	-	7	1198	4110354	77
	BX649122.1	-	7	1204		77
	DQ648895.1	-	3	271		77
	L47574.1	-	7	1224		77
	L47575.1	-	7	1222		77
	L47576.1	-	7	1223		77
	L47577.1	-	7	1224		77
	L47578.1	-	7	1224		77
	L47579.1	-	7	1224		77
	L47580.1	-	7	1224		77
	L47581.1	-	7	1224		77
	L47582.1	-	7	1224		77
	L47583.1	-	7	1224		77
	U03911.1	-	7	1187		77
	U04045.1	-	7	1252		77

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MSH2

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

meiotic mismatch repair
in utero embryonic development
oxidative phosphorylation
DNA repair
mismatch repair
postreplication repair
double-strand break repair
meiotic gene conversion
cell cycle arrest
reciprocal meiotic recombination
germ cell development
determination of adult lifespan
male gonad development
response to X-ray
response to UV-B
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
B cell mediated immunity
B cell differentiation
intra-S DNA damage checkpoint
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of neuron apoptotic process
maintenance of DNA repeat elements
negative regulation of reciprocal meiotic recombination
isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity

Function(s)

magnesium ion binding
four-way junction DNA binding
Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
double-stranded DNA binding
single-stranded DNA binding
protein binding
ATP binding
protein C-terminus binding
ATPase activity
centromeric DNA binding
enzyme binding
protein kinase binding
mismatched DNA binding
guanine/thymine mispair binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
protein homodimerization activity
ADP binding