Hs06636310_s1

• Gene Symbol: MDM2
• Gene Name: MDM2 proto-oncogene
• Gene Aliases: ACTFS, HDMX, hdm2
• Chromosome Location: Chr.12: 68808149 - 68845544 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MDM2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001145339.2	NP_001138811.1	7	924		107
	NM_001145340.2	NP_001138812.1	4	329		107
	NM_001278462.1	NP_001265391.1	4	329		107
	NM_002392.5	NP_002383.2	9	1089		107
	XM_005268872.4	XP_005268929.1	9	1017		107
	XM_006719399.3	XP_006719462.1	7	672		107
	XM_006719400.3	XP_006719463.1	8	978		107
GenBank mRNA	AF092844.1	-	7	632		107
	AF092845.1	-	8	662		107
	AF201370.1	-	2	165		107
	AF385325.1	-	4	346		107
	AF385327.1	-	3	255		107
	AK290341.1	-	9	1039		107
	AM902642.1	-	9	858		107
	AM902643.1	-	8	657		107
	AM902644.1	-	7	631		107
	AM902645.1	-	3	341		107
	AM902647.1	-	8	691		107
	AM902648.1	-	7	628		107
	AM902649.1	-	4	416		107
	AM902653.1	-	5	395		107
	AM902655.1	-	5	439		107
	AM902656.1	-	8	674		107
	AM902657.1	-	4	305		107
	AM902658.1	-	9	852		107
	AM902659.1	-	8	683		107
	AM902661.1	-	7	631		107
	AM902662.1	-	6	556		107
	AM902663.1	-	5	466		107
	AM902664.1	-	6	581		107
	AM902665.1	-	8	676		107
	AM902666.1	-	8	649		107
	AM902667.1	-	8	765		107
	AM902669.1	-	5	550		107
	AM902670.1	-	7	690		107
	AM902671.1	-	5	506		107
	AM902681.1	-	8	704		107
	BC152384.1	-	8	768		107
	BC152390.1	-	8	768		107
	BT007258.1	-	8	765		107
	EU076748.1	-	4	329		107
	GQ848196.1	-	7	690		107
	HM213901.1	-	7	604		107
	HM213902.1	-	6	470		107
	HM213903.1	-	4	416		107
	M92424.1	-	9	1076		107
	U33199.1	-	2	180		107
	U33201.1	-	3	255		107
	Z12020.1	-	9	1076		107

More Information

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MDM2

Panther Classification:

Molecular Function -

chromatin/chromatin-binding, or -regulatory protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
blood vessel development
blood vessel remodeling
regulation of heart rate
atrioventricular valve morphogenesis
endocardial cushion morphogenesis
ventricular septum development
atrial septum development
protein complex assembly
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
traversing start control point of mitotic cell cycle
positive regulation of cell proliferation
response to toxic substance
response to carbohydrate
response to iron ion
positive regulation of gene expression
negative regulation of protein processing
viral process
protein ubiquitination
protein sumoylation
peptidyl-lysine modification
protein destabilization
response to magnesium ion
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein localization to nucleus
regulation of protein catabolic process
response to cocaine
response to drug
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
response to morphine
negative regulation of DNA damage response, signal transduction by p53 class mediator
establishment of protein localization
response to ether
negative regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
response to antibiotic
positive regulation of protein export from nucleus
response to steroid hormone
cardiac septum morphogenesis
cellular response to hydrogen peroxide
negative regulation of cell cycle arrest
cellular response to antibiotic
cellular response to vitamin B1
cellular response to alkaloid
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
cellular response to estrogen stimulus
cellular response to hypoxia
cellular response to UV-C
regulation of signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator

Function(s)

p53 binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
identical protein binding
peroxisome proliferator activated receptor binding
ubiquitin protein ligase activity
scaffold protein binding