Hs06638027_s1

• Gene Symbol: ALOX12
• Gene Name: arachidonate 12-lipoxygenase, 12S type
• Gene Aliases: 12-LOX, 12S-LOX, LOG12
• Chromosome Location: Chr.17: 6993791 - 7010736 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ALOX12
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000697.2	NP_000688.2	8	1175		81
	XM_011523780.2	XP_011522082.1	7	3242		81
GenBank mRNA	BC069557.1	-	8	1153	7262463	81
	M35418.1	-	8	1163		81
	M58704.1	-	8	1155		81
	M62982.1	-	8	1175		81
	S68587.1	-	1	105		81
	S68588.1	-	1	105		81

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ALOX12

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

movement of cell or subcellular component
aging
positive regulation of cell proliferation
positive regulation of endothelial cell migration
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
positive regulation of cell growth
positive regulation of cell migration
superoxide anion generation
negative regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
linoleic acid metabolic process
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of vasodilation
positive regulation of smooth muscle cell proliferation
hepoxilin metabolic process
hepoxilin biosynthetic process
positive regulation of mitochondrial depolarization
establishment of skin barrier
cellular response to lipid
reactive oxygen species metabolic process
negative regulation of platelet aggregation
leukotriene A4 metabolic process
lipoxin metabolic process
lipoxin A4 biosynthetic process
lipoxin B4 biosynthetic process

Function(s)

arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
linoleate 13S-lipoxygenase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
hepoxilin-epoxide hydrolase activity
hepoxilin A3 synthase activity