Hs06638255_s1

• Gene Symbol: ACVRL1
• Gene Name: activin A receptor like type 1
• Gene Aliases: ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
• Chromosome Location: Chr.12: 51906913 - 51923361 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ACVRL1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000020.2	NP_000011.2	7	1097		70
	NM_001077401.1	NP_001070869.1	6	960		70
	XM_005269235.2	XP_005269292.1	8	1099		70
	XM_011539008.1	XP_011537310.1	4	643		70
GenBank mRNA	AK300619.1	-	2	78		70
	AK303331.1	-	3	355		70
	BC042637.1	-	6	846	5179243	70
	KU177888.1	-	6	814		70
	KU177889.1	-	4	502		70
	L17075.1	-	6	905		70
	Z22533.1	-	7	1096		70

More Information

Additional Information:

This assay is in the 5'UTR region of the AK300619.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ACVRL1

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

angiogenesis
in utero embryonic development
regulation of endothelial cell proliferation
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
lymphangiogenesis
blood vessel maturation
blood vessel remodeling
blood vessel endothelial cell proliferation involved in sprouting angiogenesis
endocardial cushion morphogenesis
regulation of DNA replication
regulation of transcription, DNA-templated
protein phosphorylation
negative regulation of cell adhesion
signal transduction
transforming growth factor beta receptor signaling pathway
blood circulation
regulation of blood pressure
negative regulation of cell proliferation
negative regulation of endothelial cell migration
negative regulation of gene expression
positive regulation of pathway-restricted SMAD protein phosphorylation
signal transduction by protein phosphorylation
negative regulation of cell growth
negative regulation of cell migration
BMP signaling pathway
positive regulation of BMP signaling pathway
positive regulation of chondrocyte differentiation
activin receptor signaling pathway
wound healing, spreading of epidermal cells
dorsal aorta morphogenesis
regulation of blood vessel endothelial cell migration
negative regulation of blood vessel endothelial cell migration
negative regulation of endothelial cell differentiation
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
protein heterooligomerization
negative regulation of focal adhesion assembly
lymphatic endothelial cell differentiation
artery development
venous blood vessel development
endothelial tube morphogenesis
retina vasculature development in camera-type eye
cellular response to transforming growth factor beta stimulus
cellular response to BMP stimulus
endocardial cushion to mesenchymal transition
negative regulation of DNA biosynthetic process

Function(s)

protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type I
protein binding
ATP binding
activin receptor activity, type I
protein kinase binding
SMAD binding
metal ion binding
activin binding
transforming growth factor beta binding
BMP receptor activity