Hs06639595_s1

• Gene Symbol: SORL1
• Gene Name: sortilin related receptor 1
• Gene Aliases: C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
• Chromosome Location: Chr.11: 121452203 - 121633762 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SORL1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003105.5	NP_003096.1	26	3781		100
	XM_011542963.2	XP_011541265.1	25	3542		100
	XM_011542965.2	XP_011541267.1	20	2690		100
	XM_011542967.2	XP_011541269.1	6	722		100
	XM_017018169.1	XP_016873658.1	26	3488		100
	XM_017018170.1	XP_016873659.1	24	3164		100
	XM_017018171.1	XP_016873660.1	26	3656		100
	XM_017018172.1	XP_016873661.1	12	1653		100
GenBank mRNA	AK295090.1	-	3	571		100
	AK295878.1	-	6	722		100
	AK302589.1	-	3	393		100
	BC137171.1	-	26	3704	9021168	100
	Y08110.1	-	26	3732		100

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SORL1

Panther Classification:

Molecular Function -

apolipoprotein, membrane traffic protein

Gene Ontology Categories:

Process(es)

protein targeting to Golgi
protein targeting
protein targeting to lysosome
lipid transport
post-Golgi vesicle-mediated transport
receptor-mediated endocytosis
signal transduction
cholesterol metabolic process
regulation of smooth muscle cell migration
negative regulation of protein binding
negative regulation of protein oligomerization
negative regulation of MAP kinase activity
protein retention in Golgi apparatus
positive regulation of protein catabolic process
negative regulation of neurogenesis
protein maturation
positive regulation of protein exit from endoplasmic reticulum
negative regulation of neuron death
negative regulation of beta-amyloid formation
positive regulation of choline O-acetyltransferase activity
negative regulation of tau-protein kinase activity
positive regulation of ER to Golgi vesicle-mediated transport
positive regulation of early endosome to recycling endosome transport
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
positive regulation of protein localization to early endosome
negative regulation of neurofibrillary tangle assembly
positive regulation of endocytic recycling

Function(s)

beta-amyloid binding
transmembrane signaling receptor activity
protein binding
low-density lipoprotein particle binding
ADP-ribosylation factor binding