Hs07290596_m1

• Gene Symbol: TNFSF10
• Gene Name: tumor necrosis factor superfamily member 10
• Gene Aliases: APO2L, Apo-2L, CD253, TL2, TNLG6A, TRAIL
• Chromosome Location: Chr.3: 172505508 - 172523507 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TNFSF10
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001190942.1	NP_001177871.1	2 - 3	389		65
GenBank mRNA	AK296085.1	-	2 - 3	357		65
	AY312579.1	-	2 - 3	153		65
	DQ848564.1	-	2 - 3	266		65
	EU183231.1	-	2 - 3	266		65

More Information

• Set Membership: Amplicon length less than or equal to 70, 3' Most, Homo sapiens, Probe spans exons

Gene Ontology Categories:

Process(es)

apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
immune response
signal transduction
cell surface receptor signaling pathway
cell-cell signaling
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of release of cytochrome c from mitochondria
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
regulation of extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of extrinsic apoptotic signaling pathway

Function(s)

receptor binding
cytokine activity
tumor necrosis factor receptor binding
protein binding
metal ion binding