Hs99999109_mH

• Gene Symbol: GZMB
• Gene Name: granzyme B
• Gene Aliases: CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
• Chromosome Location: Chr.14: 24630954 - 24634226 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: GZMB
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_004131.4	NP_004122.2	1 - 2	119		126
GenBank mRNA	AY372494.1	-	1 - 2	160		126
	BC030195.1	-	1 - 2	75	5223876	126
	BX283601.1	-	1 - 2	121		126
	J03189.1	-	1 - 2	92		126
	J04071.1	-	1 - 2	69		126
	M17016.1	-	1 - 2	60		126

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect transcript(s) from off target gene(s). Please contact Tech Support if you need more information.
This assay is in the 5'UTR region of the BC030195.1,J03189.1,J04071.1,M17016.1,NM_004131.4 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Protease, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene GZMB

Panther Classification:

Molecular Function -

protease, serine protease, protein modifying enzyme

Gene Ontology Categories:

Process(es)

apoptotic process
protein processing
cytolysis
natural killer cell mediated cytotoxicity
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway

Function(s)

serine-type endopeptidase activity
protein binding
serine-type peptidase activity