Mm00431646_m1

• Gene Symbol: Acvr1
• Gene Name: activin A receptor, type 1
• Gene Aliases: ALK2, ActR-I, ActRIA, Acvr, Acvrlk2, Alk-2, Alk8, D330013D15Rik, SKR1, Tsk7L
• Chromosome Location: Chr.2: 58446438 - 58566828 on Build GRCm38
• Species: Mouse
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: Acvr1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001110204.1	NP_001103674.1	9 - 10	1461		68
	NM_001110205.1	NP_001103675.1	7 - 8	939		68
	NM_007394.3	NP_031420.2	8 - 9	1216		68
GenBank mRNA	AF332087.1	-	6 - 7	849		68
	AF332088.1	-	6 - 7	849		68
	AK052246.1	-		1051		68
	AK053428.1	-	9 - 10	1460		68
	AK150014.1	-	8 - 9	1216		68
	AK150075.1	-	8 - 9	1216		68
	BC058718.1	-	6 - 7	937	6418954	68
	L15436.1	-	7 - 8	1289		68

More Information

Updated Mapping Information

This assay targets the same location as MTA transcript cluster(s) TC0200003579.mm.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Protein Kinase, Mammalian Gene Collection, Mus musculus, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene Acvr1

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

G1/S transition of mitotic cell cycle
patterning of blood vessels
urogenital system development
in utero embryonic development
gastrulation with mouth forming second
mesoderm formation
neural crest cell migration
embryonic heart tube morphogenesis
mitral valve morphogenesis
atrial septum primum morphogenesis
protein phosphorylation
transmembrane receptor protein serine/threonine kinase signaling pathway
transforming growth factor beta receptor signaling pathway
germ cell development
determination of left/right symmetry
gastrulation
mesoderm development
heart development
embryo development
negative regulation of signal transduction
positive regulation of pathway-restricted SMAD protein phosphorylation
phosphorylation
peptidyl-threonine phosphorylation
signal transduction by protein phosphorylation
regulation of ossification
positive regulation of bone mineralization
BMP signaling pathway
activin receptor signaling pathway
negative regulation of activin receptor signaling pathway
intracellular signal transduction
positive regulation of osteoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
smooth muscle cell differentiation
pharyngeal system development
pathway-restricted SMAD protein phosphorylation
cardiac muscle cell fate commitment
endocardial cushion cell fate commitment
positive regulation of determination of dorsal identity
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
transforming growth factor beta receptor activity, type I
ATP binding
kinase activity
activin receptor activity, type I
transferase activity
transferase activity, transferring phosphorus-containing groups
growth factor binding
protein homodimerization activity
SMAD binding
metal ion binding
activin binding
transforming growth factor beta binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Mouse Clariom S Array	PSR0200030477.mm.1	NM_001110204.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200030477.mm.1	NM_001110204.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200030477.mm.1	NM_001110205.1.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200030477.mm.1	NM_001110205.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200030477.mm.1	NM_007394.3.1	Refseq
Affymetrix Mouse Clariom S Array	PSR0200030477.mm.1	NM_007394.3	Refseq
Affymetrix Mouse Clariom S Array	PSR0200030477.mm.1	TC0200003579.mm.1	MTA TC